摘要
目的探讨近年来老年溃疡性结肠炎（UC）患者与非老年UC患者临床特点差异,为临床诊治老年UC患者提供经验。方法回顾性分析该院2005年1月至2012年12月收治的183例UC患者临床资料及内镜学资料。以发病年龄大于或等于60岁作为分组标准,分为老年组65例和非老年组118例。结果 UC发病高峰年龄为40~〈50岁,老年组患者腹胀、贫血较非老年组患者多见,差异有统计学意义（P〈0.05）。两组患者在腹泻、腹痛、血便、黏液便、里急后重、消瘦、发热、肠外表现、并发症、内镜下表现等方面比较,差异无统计学意义（P〉0.05）,老年组在活动期清蛋白降低者（40.00%,26/65）较非老年组（19.49%,23/118）多见（F=27.857,P=0.000）。老年组中55例（84.62%）结肠病变范围局限在脾曲以下,而非老年组患者有90例（76.27%）患者病变范围局限在脾曲以下,两组比较,差异有统计学意义（F=9.517,P=0.002）。结论在临床治疗中应重视老年UC患者的临床特点,制订个体化治疗方案。
Objective To investigate the difference of the clinical characteristics between elderly and non-elderly pa- tients with ulcerative colitis （UC） to provide the experiences for the diagnosis and treatment of elderly UC. Methods The retro- spective analysis was conducted on the clinical and endoscopic data from 183 patients with UC treated in this hospital from Jan- uary 2005 to Dceember 2012. According to the grouping standard with the onset age t〉 60 years old, the patients were divided into the elderly group （n=65, 〉1 60 years old） and the non-elderly group （n= 118, 〈60 years old）. Results The peak age of U C ranged 40-49 years old. Abdominal distension and anemia in the elderly group were more common than those in the non-elderly group, the difference between the two groups had statistical significance （P〈0.05）. There were no statistically significant differences in the aspects of diarrhea, abdominal pain,blood stool, mucus stool,tenesmus,weight loss, fever, parenteral performance, complica tions and endoscopic performances between the two goups （P〉0.05）. In the active phase, the patients with decreased albumin in the elderly group （40.00%, 26/65 ） were more than those in the non-elderly group （19.49%, 23/118, F=27.857, P=0.000）. The en- doscopic examination revealed that 55 cases （84.62%） in the elderly group and 90 cases （76.27%） in the non-elderly group had the colonic lesion range limited to under splenic flexure（F=9.517 ,P=-0.002）. Conclusion More attention should be paid to the clinical characteristics of elderly UC during the clinical treatment and the individualized treatment scheme should be formulated.
出处
《现代医药卫生》
2013年第11期1614-1615,1618,共3页
Journal of Modern Medicine & Health
