摘要
目的探讨临床上检测尿微量白蛋白对糖尿病肾病(Diabetic nephropathy,DN)患者早期诊断的意义。方法采集标本,运用放射免疫方法,检测90例DN患者(研究组)的尿微量白蛋白含量,并与80例健康体检者(对照组)比较。结果研究组的尿微量白蛋白含量为(56.74±5.87)mg/L,明显高于正常对照组的(11.26±3.75)mg/L,两组比较差异有统计学意义(P<0.05)。不同性别患者尿微量白蛋白比较,差异无统计学意义(P>0.05)。不同病程患者的尿微量白蛋白含量比较,差异有统计学意义(P<0.05)。结论对糖尿病肾病患者早期进行尿微量白蛋白检测有助于早期判断糖尿病肾脏的损害,对糖尿病肾病患者早期发现、诊断和治疗具有重要价值。
Objective To investigate the clinical value and significance of urinary microalbumin detection for the early diagnosis in patients with diabetic nephropathy. Methods By mdioimmunoassay, urinary microalbumin content were detected in 90 patients with diabetic nephropathy （the study group） and 80 healthy individuals （the control group）. Results Urinary albumin content of the study group was （56.74±5.87） rag/L, which was significantly higher than that of the control group （11.26±3.75） mg/L. The difference was statistically significant （P〈0.05）. The difference in urinary mi- croalbumin between different genders was not statistically significant （P〉0.05）, while the difference of urinary albumin content between different course of patients was statistically significant （P〈0.05）. Conclusion The urine microalbumin detection can be used as sensitive indicators for the early diagnosis of diabetic nephropathy, which contributes to the early evaluation of diabetic kidney damage and has an important value for early detection.
出处
《海南医学》
CAS
2013年第13期1958-1960,共3页
Hainan Medical Journal
关键词
尿微量白蛋白
糖尿病肾病
检测
诊断
Urinary miemalbumin
Diabetic nephropathy
Detection
Diagnosis
