摘要
以生物可降解材料聚羟基丁酸酯(PHB)为原料,采用静电纺丝技术制备了PHB纳米纤维,利用扫描电子显微镜观察纤维形态,研究静电纺丝参数对纳米纤维直径的影响。在响应面法的Box-Behnken设计的基础上对PHB静电纺丝纤维直径进行预测,通过回归分析建立二次多元模型。结果表明,PHB溶液浓度、挤出率和浓度二次项对纤维的影响最为显著,其次是毛细管直径和毛细管直径的二次项。模型预测的纤维直径与真实值差异不显著,说明回归模型拟合情况良好,可以有效地预测静电纺PHB纤维的直径。
Polyhydroxyburyrate （PHB） nanofiber was fabricated by electrospinning technology. The morphology of the PHB nanofiber was investigated by scanning electron microscopy （SEM）. A response surface methodology （RSM） was applied to analyze the effect of electrospinning parameters on the diameter of PHB nanofiber. The Box- Benkhen experimental design （BED） technique was used to predict the diameter of electrospun PHB nanofiber. The multiple regression model was set up by regression analysis. The results show that the concentration, infusion rate and square of concentration have the most significant influence on the diameter of the nanofiber. The second important parameters are nozzle diameter and square of nozzle diameter. There are no obvious differences between the actual values and predicted values from regression equation, which means good reliability of the model.
出处
《高分子材料科学与工程》
EI
CAS
CSCD
北大核心
2013年第7期118-122,共5页
Polymer Materials Science & Engineering
基金
天津市自然科学基金(11JCYBJC02500)
