摘要
目的:评估VIP方案化疗与放射治疗晚期非小细胞肺癌(NSCLC)的近期疗效。方法:观察1997年2月～1999年2月收治的33例晚期非小细胞肺癌患者。化疗以VIP方案为主,2～4周期后行放射治疗,放疗剂量DT 50～70Gy/5～7周。结果:完全缓解(CR)率为15.2％,部分缓解率(PR)为51.5％,总有效率(CR+PR)为66.7％。毒副反应主要为Ⅰ～Ⅱ度消化道反应、骨髓抑制及脱发。结论:VIP方案化疗加放疗治疗晚期非小细胞肺癌的近期疗效较为满意,毒副反应患者可以耐受。
Objective: To evaluate the short term response of chemotherapy in combination with radiotherapy for advanced non-small cell lung cancer(NSCLC) . Methods: From February 1997 through February 1999, 33 patients with advanced NSCLC were entered into the study. The major regimn of chemotherapy was VIP, radiotherarpy was given after 2 ~ 4 cycles of the chemotherapy. The radiation does ranged from 50~70Gy/5~7 weeks. Results:The complete response(CR) rate was 15.2%, and partial response (PR) was 51.5%, the overall effective (CR+ PR) rate was 66.7% . The major toxic effects were gastrointerstinal tract reactions, myelosuppression and alopecia. Conclusions:The short term response of VIP regimen chemotherapy combination with radiotherapy for patients with advanced NSCLC is prefirable and tolerable toxicity.
出处
《临床肿瘤学杂志》
CAS
2000年第3期190-191,共2页
Chinese Clinical Oncology
关键词
VIP方案化疗
放疗
晚期非小细胞肺癌
VIP Chemotherapy Radiotherapy Advanced non small cell lung cancer
