摘要
目的研究肺癌患者凝血功能及影响凝血的相关指标。方法我院收治的初诊肺癌患者217例,以100例健康人为对照组,进行凝血指标的检测,研究肺癌患者纤维蛋白原、血小板在不同年龄、性别、是否合并基础疾病、PS评分、病理类型及分期的差异。结果 (1)肺癌患者纤维蛋白原、血小板显著高于对照组,P<0.05。(2)肺癌患者的FIB在年龄>60岁、合并基础疾病、PS评分>2分及Ⅲ、Ⅳ期患者中有明显升高,P<0.05;在患者性别、不同病理类型中无明显统计学差别,P>0.05。(3)肺癌患者的血小板计数在不同年龄、是否合并基础疾病、PS评分、肺癌病理类型及分期等方面均无明显差异,P>0.05。结论肺癌患者存在高凝状态,年龄>60岁、合并基础疾病、PS评分>2分及Ⅲ、Ⅳ期患者为高危患者。
Obejective To study the state of coagulation function and the related factors in patients with lung cancer.Methods 217 patients with lung cancer were selected as the study group,and 100 healthy people were taken as the control group.The indexes of blood coagulation were detected to compare the differences of the levels of FIB and PLT in lung cancer patients on age,sex,primary diseases,performance status score and pathological stages and types.Results（1） The levels of FIB and PLT were significantly higher in the study group than in the control group（P〈0.05）.（2） The level of FIB were obviously higher in patients with older than 60 years,primary diseases,PS score more than 2,and Ⅲ or Ⅳ stage（P〈0.05）,but there was no correlation in lung cancer patients on FIB and sex,and pathological types（P〈0.05）.（3） The levels of PLT had no difference in all kinds of lung cancer patients（P〈0.05）.Conclusion There exists hypercoagulability in patients with lung cancer,and the high risk factors include age older than 60-year-old,PS score more than 2,primary diseases,and patients at Ⅲ or Ⅳ pathological stages.
出处
《临床肺科杂志》
2013年第8期1492-1493,共2页
Journal of Clinical Pulmonary Medicine
关键词
肺癌
凝血功能
多因素分析
lung cancer
coagulation function
multivariate analysis
