摘要
目的:观察异丙嗪联合葛根素治疗急诊眩晕的临床疗效及安全性。方法:选取我院自2009年5月至2012年3月收治的98例急诊眩晕患者作为研究对象,按照随机数字表法随机分为观察组与对照组各49例,观察组给予异丙嗪联合葛根素治疗,对照组给予异丙嗪联合地西泮治疗,比较两组患者的临床疗效及不良反应情况。结果:①观察组总有效率为89.8%,对照组总有效率为73.5%,观察组总有效率明显高于对照组(X2=14.273,P<0.01),具有统计学意义。②观察组眩晕、恶心呕吐、耳鸣耳聋消失时间均较对照组明显缩短(P<0.01),出汗消失时间无明显差异(P>0.05)。③观察组不良反应包括困倦2例、口干1例;对照组不良反应包括困倦3例,嗜睡1例,口干1例。两组患者不良反应发生率无明显差异(P>0.05),无统计学意义。结论:异丙嗪联合葛根素治疗急诊眩晕效果理想,可以迅速改善临床症状,且安全性较高,值得临床推广应用。
Objective： To observe the clinical efficacy and safety of promethazine combined with puerar in in treating emergency vertigo. Method： 98 patients with emergency vertigo treated in our hospital from May 2009 to March 2012 were selected. They were divided into 2 groups according to randomly digital table, the observation group and the control group, each group for 49 cases. The observation group were treated with promethazine combined with puerarin, and the control group were treated with promethazine combined with diazepam Clinical efficacy and adverse reactions of 2 groups were compared. Results： The total ef fective rate of the observation group was 89.8%, and the total effective rate of the control group was 73. 5%. The total effective rate of the observation group was higher evidently than that of the control group（ X2 = 14.273, P〈0.01 ） , which had statistical significance. The time of vertigo, nausea and vomit, tinnitus and deafness disappearing in the observation group was shorter than that in the control group （ P〈0.01 ）. And there was no evident difference in the time of sweat disappearing （ P〉0.05 ）. As for the adverse reactions in the observation group, there were 2 cases with drowsiness and 1 case with dry mouth. And there were 3 cases with drowsiness, 1 case with sleepiness and 1 case with dry mouth. The incidence rate of adverse reac tions in 2 groups had no evident difference（ P〉0.05 ）, which had no statistical significance. Conclusion： Promethazine combined with puerarin in treating emergency vertigo has ideal effect, can improve the clinical symptoms rapidly and has higher safety, which is worthy to be applied and promoted in clinical practice.
出处
《河北医学》
CAS
2013年第8期1165-1167,共3页
Hebei Medicine
关键词
急诊眩晕
异丙嗪
葛根素
Emergency vertigo
Promethazine
Puerarin
