摘要
目的观察生金平喘汤联合西医常规治疗毛细支气管炎的临床疗效。方法将200例毛细支气管炎患儿随机分为2组。对照组99例予西医常规治疗,治疗组101例在对照组治疗基础上予生金平喘汤加味治疗。观察2组治疗后症状、体征恢复时间,住院天数以及治疗前后血白细胞介素-13(IL-13)、肿瘤坏死因子α(TNF-α)、尿白三烯E4(LTE4)变化情况。结果治疗组治愈率61.39%,总有效率92.08%,对照组治愈率41.41%,总有效率78.79%,2组比较差异均有统计学意义(P<0.05)。治疗组咳嗽好转时间、喘憋缓解时间、肺部体征消失时间及住院天数均短于对照组(P<0.05)。治疗组治疗后IL-13、TNF-α、尿LTE4较治疗前降低(P<0.05),与对照组治疗后比较差异均有统计学意义(P<0.05)。结论生金平喘汤联合西医常规治疗毛细支气管炎疗效确切。
Objective To investigate the effect of Shengjinpingchuan decoction on the treatment of capillary bronchitis. Methods 200 children with capillary bronchitis were randomly divided into two groups. 99 children in control group were treated by conventional western medicine. 101 cases in treatment group were treated by Shengjin- pingchuan decoction on the basis of control treatment. Recovery time of symptoms and signs, hospital stay after treat- ment were observed. The changes of IL - 13 ,TNF -sand urine LTE4 were recorded before and after treatment. Re- sults The cure rate and the total effective rate in treatment group（61.39% ,92.08% ） were higher than that in con- trol group（41.41% ,78.79% ）. There was statistically significant differences between two groups（P 〈0.05）. Improved time of cough, wheezing relief time,pulmonary signs disappear time and length of hospital stay in treatment group was superior to that in control group（ P 〈 0. 05 ）. IL - 13, TNF -α and urine LTE4 after treatment were de- creased as compared with those before treatment in treatment group（P 〈 0. 05）. Conclusion Shengjinpingchuan de- coction has definite effect on the treatment of capillary bronchitis.
出处
《河北中医》
2013年第6期866-868,共3页
Hebei Journal of Traditional Chinese Medicine
关键词
毛细支气管炎
中西医结合疗法
Capillary bronchitis
Combined therapy of Chinese and Western medicine
