摘要
本文报告我院1983年1月～1990年6月间收治的肺心病患者980例,其中发生多器官衰竭者154例,死亡114例,病死率74％。累及器官除心肺外有脑、肝脏、胃肠道、肾脏和血液系统。讨论了肺心病并多器官衰竭发病年龄较大,年龄愈大累及器官愈多死亡率愈高,感染是诱发多器官衰竭的主要因素,特别是革兰氏阴性杆菌的感染。在多器官衰竭的防治方面,积极有效控制感染是治疗的关键,青霉素联用头孢菌素类抗生素效果较好。但在使用抗生素治疗时应注意氨基甙类抗生素的毒副作用,累及肾脏和血液系统属诸器官衰竭的晚期,不易救治。高频喷射呼吸机基本不适用于肺心病并多器官衰竭的治疗。
in the period from Lanuary, 1983 to June, 1990, a total of 980 cases of cor pulmonale were hospitaluzed in this institute. Among the 980, 154 cases were complicated with multiple organ failure (MOF), and 114 cases out of the 154 died with a mortality rate of 74%. Besides the heart and the lungs, the organs involved were the brain, the liver, the gastrointestinal tract, the kidneys and the blood system. It was found that MOF more often occurred in elderly persons. The older the patient is, the more the organs will be involved and the higher the mortality rate will be. Infection especially that of gram negative bacilli was the main factor to induce MOF. The combined administration of penicillin and the antibiotics of cephalosporin group was quite helpful to control the infections, which is the key step in the management of such cases, when the antibiotics of aminoglycoside group were used, special attention must be paid to the prevention of their toxic effects on the kidneys High-frequency jet ventilation is not suitable to treat cor pulmonale complicated with MOF.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1991年第3期243-246,共4页
Journal of Third Military Medical University
关键词
肺心病
药物疗法
多器官衰竭
pulmonale heart disease
multiple organ failure
