摘要
目的:采用响应面法优选毛脉酸模多糖提取工艺。方法:采用Box-Behnken的中心组合实验设计原理优化毛脉酸模多糖提取方法。结果:得到最佳工艺条件是:提取时间2.9h,粉碎粒度为120目,醇沉浓度为70%,重复3次,得到多糖的得率最高为7.12%。结论:采用响应面法优化得到的提取毛脉酸模多糖参数准确可靠,具有实用价值。
Objective：The experient used response surface methoddogy（RSM） to optimize the best Rumex gmelini polysaccharide extraction conditions.Methods：Box-Behnke statistical design technology was used to optimize the method of Rumex gmelini polysaccharide extraction.With the response surface optimization,the optimum conditions were：extraction time 2.9h;the grinding particle size was 120 mesh;the alcohol precipitation concentration was 70% and the decoction was carried out for three times,and its gotten rate was about 7.12%.Conclusion： By using the response surface method the parameters of optimized extraction of Rumex gmelini polysaccharide are accurate and reliable,and have a practical value.
出处
《中医药学报》
CAS
2013年第3期48-52,共5页
Acta Chinese Medicine and Pharmacology
基金
国家自然科学基金(No.30970300)
哈尔滨市科技创新人才研究专项资金(No.2010RFXXS031)
关键词
响应面
毛脉酸模
多糖
提取工艺
Response surface method
Rumex gmelini
Polysaccharide
Extraction technology
