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丹参酮ⅡA磺酸钠注射液治疗急性脑梗死的疗效及其对血清D-二聚体的影响 被引量:8

The curative effect of tanshinone II A sodium sulfonate injection on acute cerebral infarction and the effect which to D-dimeric.
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摘要 目的观察丹参酮ⅡA磺酸钠注射液对急性脑梗死患者的疗效及血清D-二聚体的影响。方法采用丹参酮ⅡA磺酸钠注射液静脉滴注治疗急性脑梗死40例(治疗组),维脑路通静脉滴注治疗急性脑梗死40例(对照组)。比较2组的临床疗效和治疗前后患者血清中D-二聚体的含量变化。结果治疗组及对照组总有效率分别为92.5%和80.0%,2组疗效比较差异有统计学意义(P<0.05)。2组患者血浆D-二聚体含量均明显下降;治疗组较对照组血浆D-二聚体含量下降更明显(P<0.05)。结论丹参酮ⅡA磺酸钠注射液治疗急性脑梗死有利于早期恢复脑血供,改善微循环,降低D-二聚体含量,调节体内凝血-纤溶系统功能平衡,促进患者康复,安全性好。 Objective To observe the curative effect of tanshinone II A sodium sulfonate injection on acute cerebral infarction and the effect which to D-dimeric.Methods The treat group using tanshinone II A sodium sulfonate injection and the control group using troxerutin. And to compare the clinic curative effect between the two groups and the changes of D-dimeric content in serum after treatment. Results The total effective rate of treat group was 92.5% and the other was 80.0%(P0.05). The D-dimeric content in serum in the two groups were decreased obviously; it was more desereded obviously in the treat group than the control group(P0.05).Conclusion The tanshinone II A sodium sulfonate injection which treat on acute cerebral infarction can advance blood supply to brain early recovery, improve microcirculation and degrade the D-dimeric content and promote patient recovered.
作者 苏萍
出处 《中国实用医药》 2013年第16期49-50,共2页 China Practical Medicine
关键词 脑梗死 丹参酮ⅡA磺酸钠注射液 D-二聚体 Cerebral infarction Tanshinone II A sodium sulfonate injection D-dimeric
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