摘要
目的观察无创正压通气联合可拉明治疗慢性阻塞性肺疾病(COPD)合并肺性脑病的治疗效果。方法 40例COPD合并肺性脑病患者随机分为2组,每组20例,对照组予常规治疗,治疗组在常规治疗基础上应用无创正压通气同时维持静脉滴注可拉明。比较2组患者的意识转清时间、住院时间、气管插管率、治疗前后动脉血气分析情况。结果治疗组治疗后意识转清时间和住院时间均较对照组明显缩短,2组比较均有显著性差异(P<0.01);治疗组治疗后气管插管率较对照组明显减少,2组比较有显著性差异(P<0.05);治疗组在治疗后6 h和24 h血气分析情况较对照组明显改善,2组比较有显著性差异(P<0.01)。结论在常规治疗COPD合并肺性脑病的基础上使用无创正压通气联用可拉明可以获得较好的治疗效果,能有效缩短患者意识转清时间和住院时间,降低气管插管率,迅速改善血气分析情况。
Objective To observe the effect of noninvasive positive pressure ventilation（NPPV）combined with maintaining intravenous drip of Coraminum on treatment of COPD complicating pulmonary encephalopathy（PE）based on routine treatment.Methods 40 patients with COPD complicating PE were randomly divided into treatment group and control group,with 20 patients in each group.The treatment group,based on routine treatment,was treated with NPPV combined with maintaining intravenous drip of Coraminum,while the control group was treated with routine treatment.The time of consciousness recovering,the rate of trachea cannula and hospital stays of both groups were observed,and arterial blood gas（ABG）before and after treatment were determined in both groups.Results After treatment,compared with the control group,the time of consciousness recovering in treatment group was much shorter,with significant statistical difference（P0.01）;the rate of trachea cannula was significantly lowe（r P0.01）;the ABG were improved much better than that of control group（P0.05）;and the hospital stays in treatment group were shorter（P0.01）.Conclusion Based on NPPV,Coraminum can effectively shorten the time of consciousness recovering,reduce the rate of trachea cannula,improve ABG and shorten the hospital stays in patients with COPD complicating PE.
出处
《基层医学论坛》
2013年第17期2187-2189,共3页
The Medical Forum
关键词
慢性阻塞性肺疾病
肺性脑病
无创正压通气
可拉明
Chronic obstructive pulmonary disease Pulmonary encephalopathy NIPPV Coraminum
