摘要
目的探讨口服孟鲁司特预防毛细支气管炎后反复喘息的效果。方法将87例临床治愈出院的毛细支气管炎患儿随机分成干预组(46例)和对照组(41例)。干预组给予孟鲁司特口服,1次/d,4mg/次,持续3个月;对照组治愈出院后未予任何治疗。随访观察1年两组喘息再发作的情况。结果干预组再发喘息率明显低于对照组(P<0.01或<0.05)。结论口服孟鲁司特可预防毛细支气管炎后反复喘息及预防哮喘的发生。
Objective To evaluate the effect of oral montelukast in preventing asthma attack after bronchili- tis. Methods Eighty-seven bronchilitis infants were divided randomly into intervention group （ n = 46） and control group, two groups （n = 41 ） received conventional therapy, and the interventiong group was given oral montelukast （4 mg daily for 3 months） on the basis of above therapy. Infants were followed up for 1 year, the effect on asthma attack 1 year after the treatment were observed and compared. Results The recurrent rates of asthma of the intervention group were lower than that of the control group （P 〈 0. 01 or P 〈 0. 05 ）. Conclusion The oral montelukast can reduces the recurrences of asthma attacks after bronchilitis, asthma might be prevented.
出处
《中国临床新医学》
2013年第6期564-566,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
