摘要
目的:了解2012年广东省深圳市宝安区病毒性腹泻标本中轮状病毒、诺如病毒、星状病毒和肠道腺病毒流行现况,为病毒性腹泻的诊治提供依据。方法:收集整理哨点医院上报的数据,采用实时荧光定量-聚合酶链反应对2012年1～12月深圳市371例疑似腹泻患者粪便标本同时进行轮状病毒(rotavirus,RV)、诺如病毒(norovirus,NV)、星状病毒(astrovirus,AstV)和肠道腺病毒(enteric adenovirus,EAdV)核酸检测,并进行统计分析。结果:371例标本总的病毒检出率为48.25%。4种常见腹泻病毒的检出率分别为28.84%、17.25%、1.35%和1.35%。RV和NV全年除2月外其余各月均维持较高的检出率,EAdV与AstV的检出率均维持相对较低水平。0～2岁年龄组患者的感染率显著高于3岁以上年龄组患者。结论:2012年深圳市宝安区病毒性腹泻呈高发状态,其中RV和NV是主要的病原之一,并且主要集中在3岁以下儿童和20岁以上成人。RV感染有明显的季节特征,秋冬季为发病高峰;NV感染则无特殊的季节特征,应对病毒性腹泻加强长期监测。
Objective：To understand the Guangdong province Shenzhen Baohn district 2012 viral diarrhea rotaviros in specimens, such as RV, NV, AstV and EAdV of epidemic, and provide the basis for the diagnosis and treatment of viral diarrhea. Methods： Collect sentinel hospitals reported data, model using real - time fluorescence quantitative polymerase chain reaction for January 2012 - December 371 suspected of Shenzhen stool specimens sim- ultaneously rotavirus diarrhea patients （ rotavirus, RV）, such as virus （ norovirus, NV）, star（ astrevirus, AstV） and the enteric adenovirus （ enteric odenovi- rus, EAdV） nucleic acid detection, and statistical analysis. Results： Specimens of 371 cases of total virus detection rate is 48.25 %. Four kinds of common diarrhea virus detection rate of 28.84% , 17.25% , 1.35% and 1.35% respectively. Rotavirus and virus, such as whole year except February the rest every month to maintain a higher detection rate, enteric adenovirus and stellate virus detection rates remain relatively low. 0 - 2 years old age group of patients with infection rates were significantly higher in patients with more than 3 years old age group. Conclusion：2012 Shenzhen Bao＇an viral diarrhea in high- risk state,including rotavirus and novartis is one of the major pathogens such as viruses, and mainly in children under 3 years old and adults over the age of 20. Rotavirus infection have obvious seasonal characteristics, fall and winter as the peaks;Noroviros infection have no special seasonal characteristics, should strengthen the long - term monitoring of viral diarrhea.
出处
《中国民康医学》
2013年第12期1-3,82,共4页
Medical Journal of Chinese People’s Health
基金
2011年深圳市宝安区科技创新局资助项目(20110597)
