摘要
目的了解我院60岁及以上老年住院患者抗菌药物的使用情况,评价其用药合理性。方法回顾性分析我院2011年7—12月使用抗菌药物的老年患者出院病历资料758份并进行统计分析。结果共调查1 137份老年出院患者病历,758例使用了抗菌药物,使用率为66.67%,其中联合用药占63.06%(478/758)。使用例次居前3位的药物种类分别是:头孢菌素类(35.16%,596/1 695)、β-内酰胺酶抑制剂复方制剂(21.71%,368/1 695)、喹诺酮类(18.70%,317/1 695);使用例次居前3位的药品分别为:注射用阿莫西林钠克拉维酸钾(19.40%,221/1 139)、头孢地尼胶囊(15.01%,171/1 139)、注射用头孢地秦钠(12.91%,147/1 139)。44.99%(341/758)做了一般细菌培养及鉴定,31.13%(236/758)做了常规药敏试验。用药不合理的典型病历117份,占总病历数的15.44%。结论我院老年住院患者抗菌药物的使用存在不合理性。抗菌药物合理使用仍需进一步规范。
Objective To evaluate the use of antibacterial drugs among inpatients over 60 years in our hospi- tal. Methods Medical records of discharged patients who used antibacterial drugs between July and December 2011 were retro- spectively studied. Results Totally 758 out of 1 137 （66. 67% ） medical records we investigated had used antibacterial drugs, with combination therapy accounting for 63.06% （478/758）. The top three antibacterial drug types regarding person -time use were cephalosporin （596/1 695, 35. 16% ）, β[3 - lactam/β - lactamase inhibitor （368/1 695, 21.71% ）, and quinolones （317/1 695, 18.70% ）. The top three antibiotic agents were amoxicillin sodium and clavulanate potassium for injection （221/ 1 139,19.40% ）, cefdinir capsule （ 171/1 139, 15.01% ）, and cefodizime sodium for injection （ 147/1 139, 12.91% ）. A- mong the 758 eases, 44. 99% （341/758） used bacterial culture and identification, and 31.13% （236/758） used susceptibility testing. Irrational drug use occurred in 117 cases, accounting for 15.44% of the total. Conclusion There is the irrationality in antibacterial drug use among the older inpatients in our hospital. Antibacterial drugs should be used with more caution and ration- ality in the future.
出处
《中国全科医学》
CAS
CSCD
北大核心
2013年第16期1910-1913,共4页
Chinese General Practice
关键词
抗菌药物
用药分析
老年
住院患者
Antibacterial drugs
Analysis of drug use
Aged
Inpatients
