期刊文献+

氯吡格雷联合阿司匹林治疗急性冠状动脉综合征的效果观察 被引量:4

暂未订购
导出
摘要 目的探讨氯吡格雷联合阿司匹林治疗急性冠状动脉综合征(ACS)的疗效。方法将ACS患者90例随机分为两组,各45例。对照组给予阿司匹林肠溶片治疗,观察组给予氯吡格雷联合阿司匹林肠溶片治疗,比较两组的临床疗效。结果观察组总有效率高于对照组(P<0.05);观察组血小板凝集率低于对照组(P<0.01),两组患者在治疗期间均未出现严重不良反应。结论氯吡格雷联合阿司匹林治疗ACS疗效显著,可有效降低血小板凝集率,且安全可靠,值得临床推广应用。
作者 杨丽娜 李涛
出处 《白求恩军医学院学报》 2013年第3期249-250,共2页 Journal of Bethune Military Medical College
  • 相关文献

参考文献3

二级参考文献13

  • 1王彦昌,冯培青.噻氯匹定对冠心病病人血小板聚集的抑制作用[J].新药与临床,1997,16(1):41-42. 被引量:9
  • 2Shim CY,Yoon SJ,Park S,et al.The clopidogrel resistance can be attenuated with triple antiplatelet therapy in patients undergoing drug-eluting stents implantation[J].Int J Cardiol,2009,134(3):351-355.
  • 3Gibson CM,Cannon CP,Muphy SA,et al.Relationship of TIMI myocardial perfusion grade to mortality after administration of thrombolytic drugs[J].Circulation,2000,101 (2):125-130.
  • 4Smith SC Jr,Feldman TE,Hirshfeld JW Jr,et al.ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention:a report of the american college of cardiology/american heart association task force on practice guidelines (ACC/AHA/SCAI writing committee to update 2001 guidelines for percutaneous coronary intervention)[J].Circulation,2006,113(7):166-286.
  • 5Van't Hof AW,Valgimigli M.Defining the role of platelet glycopretein recertor inhibitors in STEMI:focus on tirofiban[J].Drugs,2009,69(1):85-100.
  • 6De Luca G,Smit JJ,Ernst N,et al.Impact of adjunctive tirofiban administration on myocardial perfusion and mortality in patients under-going primary angioplasty for ST-segment elevation myocardial infarction[J].Thromb Haemost,2005,93(5):820-823.
  • 7Van't Hof AW,Ten Berg J,Heestermans T,et al.Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty(On-TIM 2):a multicentre,double-blind,randomised contyolled trial[J].Lancet,2008,372(9638):537-546.
  • 8Cuisset T,Hamilos M,Sarma J,et al.Relation of low response to clopidogrel assessed with point-of-care assay to periprocedural myonecrosis in patients undergoing elective coronary stenting for stable angina pectoris[J].Am J Cardiol,2008,101(12):1700-1703.
  • 9Alpert JS,Thygesen K,Jaffe A,et al.The universal definition of myocardial infarction:a consensus document:ischaemic heart disease[J].Heart,2008,94(10):1335-1341.
  • 10Sabatine MS,Morrow DA,Giugliano RP,et al.Implications of upstream glycoprotein IIb/IIIa inhibitor and coronary artery stenting in the invasive management of unstable angina non-ST-elevation myocardial infarction:a comparison of the thrombolysis in myocardial infarction (TIMI) IIIB trial and the treat angian with aggrastat and determine cost of therapy with invasive or conservative strategy(TACTICS)-TIMI 18 trial[J].Circulation,2004,109(7):874-880.

共引文献9

同被引文献44

引证文献4

二级引证文献85

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部