摘要
原发性中枢神经系统淋巴瘤(primary central nervous system lymphoma,PCNSL)是罕见的起源于中枢神经系统的非霍奇金淋巴瘤。无论在免疫功能正常人群或在免疫功能缺陷人群中,其发病率都在逐年上升。文中主要综述发生于免疫功能正常人群的PCNSL的流行病学、病理学及医学影像学特征。PCNSL具有某些特征性的影像表现,将传统医学影像手段(如CT、MRI)与新兴医学影像学技术相结合,如弥散加权成像(diffusion weighted imaging,DWI)、灌注加权成像(perfusionweighted imaging,PWI)、磁共振波谱分析(magnetic resonance spectroscopy,MRS)及18氟-脱氧葡萄糖(18F-fluorodeoxyglucose,18F-FDG)PET/CT等,能大大提高PCNSL的诊断水平。
Primary central nervous system lymphoma （PCNSL） is a rare non-Hodgkin′s lymphoma arising in the central nervous system, and its incidence is on the rise both in immunocompetent individuals and immunodeficient patients. This review focuses on the epidemiology, pathogenesis and imaging diagnosis of this aggressive extranodal lymphoma in immunocompetent patients. PCNSL has some characteristic imaging features, and accordingly its diagnosis can be largely improved by conventional CT and MRI combined with advanced imaging techniques, including diffusion weight imaging, perfusion weight imaging, 1H-MR spectroscopy and 18F-FDG PET/CT.
出处
《医学研究生学报》
CAS
北大核心
2013年第6期629-633,共5页
Journal of Medical Postgraduates
基金
国家自然科学基金重大国际合作项目(81120108013)
