摘要
目的 观察帕金森病 (PD)患者认知功能障碍并对其相关因素进行分析。方法 采用龚氏修订的韦氏成人智力量表 (WAIS- RC) ,对 4 0例 PD患者进行测试 ,并与病程、运动功能障碍、受教育年限等因素进行相关性分析。结果 PD组言语部分各分测验成绩均显著低于对照组 ;PD组操作智商 (PIQ)的平均值低于言语智商 (VIQ)的平均值 ;PD组患者病程与各分测验无相关关系 ,运动功能障碍与各分测验有负相关关系 ,受教育年限与知识、领悟、相似性、词汇、填图有密切相关关系。结论 PD患者在认知功能的诸多方面均有障碍 ,PD患者在操作方面损害比言语方面更明显。 PD患者病程对其认知功能无明显影响 ,而运动功能障碍、受教育年限对认知功能影响均较显著。
Objective To observe the cognitive impairment in patients with Parkinson disease (PD) and analyse its correlative factors.Methods Forty patients with PD were tested with WAIS RC and analysed on the ralation between WAIS RC scores and the course of PD,motor dysfunction and education.Results Psychometry revealed that in PD group the scores of every tests in verbal part were significantly lower than that in control group,and the average value of performance QI was less than that of verbal IQ in PD group.There was no correlation between the course of PD with the scores of every test,whereas motor dysfunction had negative correlations with the scores of every test.The duration (years) of education had close relation with knowledge,apperception,similarity,vocabulary and the aptitude of figure filling in.Conclusions There exist impediments in many aspects of the cognition in patients with PD,and the impairment in performance is more evident than in verbal,which indicated that there is definitely intellectual deterioration of cortical and subcortical types.The course of PD exert no influence on the cognition,but motor dysfunction and duration of education have much notable effect on the cognitive function.
出处
《北京医学》
CAS
北大核心
2000年第4期198-201,共4页
Beijing Medical Journal
