摘要
目的:了解某三级甲等医院妇产科Ⅱ类切口手术围术期预防性应用抗菌药物情况,为临床合理用药提供参考。方法:抽取该院会阴切开术、全子宫切除术、子宫肌瘤切除术、剖宫产手术、双附件切除术病历各40份,回顾性分析其预防性应用抗菌药物情况,并评价其合理性。结果:该院妇产科200例Ⅱ类切口手术患者,有190例围术期预防性应用了抗菌药物,预防性使用率为95.00%;平均预防性用药疗程为(3.77±1.37)d;选用的抗菌药物主要为头霉素类、硝基咪唑类和头孢菌素类。不合理用药主要表现为给药时间不当、联合用药不当、疗程偏长、溶剂用量偏大、选药不当等。结论:该院妇产科Ⅱ类切口手术围术期预防性应用抗菌药物不合理现象的比例较高,应采取有效的干预措施,提高合理用药水平。
OBJECTIVE： To investigate the perioperative use of prophylactic antibiotics for obstetric and gynecologic patients undergoing type Ⅱ incision surgery in a three-a grade hospital for reference of clinical rational use of drugs. METHODS：The medical records of patients undergoing episiotomy, panhysterectomy, hysteromyomectomy, cesarean section and bilateral adnexectomy （40 cases for each kind of operation）were sampled for retrospective analysis regarding the prophylactic use of antibiotics with its rationality evaluated as well. RESULTS ： Of the total 200 cases reviewed,190（95.00% ）had perioperative use of prophylactic antibiotics for an average duration of（3.77 ± 1.37） days. The main types of antibiotics used included cephamycin, nitroimidazoles and cephalosporins. The non-rational useof drugs manifested as improper administration time, improper drug combination, prolonged course of treatment, large dose of solvents and improper choice of drugs etc. CONCLUSION： The irrational perioperative use of prophylactic antibiotics for obstetric and gynecologic patients undergoing type Ⅱ incision surgery in a hospital showed high proportion, thus effective intervention measures should be taken to improve the level of rational use of drugs.
出处
《中国医院用药评价与分析》
2013年第5期422-424,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
抗菌药物
Ⅱ类切口手术
围术期
妇产科
Antibiotics
Type Ⅱ incision surgery
Perioperative period
Obstetric and gynecologic department
