摘要
目的评价纤维支气管镜和支气管肺泡灌洗治疗难治性肺炎的临床疗效和安全性。方法选择浙江省东阳市中医院2010年3月～2012年9月接受纤维支气管镜和支气管肺泡灌洗治疗的难治性肺炎患者63例为治疗组,选择同期住院但不接受该项检查和治疗的难治性肺炎患者45例为对照组。比较两组患者总有效率、住院天数、治疗费用、不良反应等方面的差异,评价纤维支气管镜和支气管肺泡灌洗在难治性肺炎中的应用价值。结果治疗组总有效率为98.4%(62/63),对照组总有效率为73.3%(33/45),差异有统计学意义(P<0.05)。治疗组和对照组的住院时间分别为(19.69±3.72)d、(27.35±8.06)d,治疗组的住院时间明显短于对照组;治疗组的平均治疗费用(3.42±1.64)万元,对照组平均治疗花费(8.53±3.73)万元,治疗组的平均治疗费用低于对照组,差异有统计学意义(P<0.05)。治疗组未出现严重并发症。结论纤维支气管镜和支气管肺泡灌洗治疗难治性肺炎,无严重不良反应发生,是难治性肺炎患者的经济、有效、安全的选择。
Objective To evaluate the clinical efficacy and safety analysis on fiberoptic bronchoscopy and bronchial lavage in the treatment of refractory pneumonia.Methods 63 patients with refractory pneumonia who accepted the fiber bronchoscopy examination and broncho alveolar lavage in Traditional Chinese Hospital of Dongyang City from March 2010 to September 2012 were selected as treatment group,45 patients with refractory pneumonia who refused the fiber bronchoscopy examination in the same term were picked as control group.Total effective rate,length of hos pital stay,cost of treatment and adverse reaction were compared in treatment group and control group to estimate the application value in refractory pneumonia patients.Results Total effective rate in treatment group was 98.4%（62/63）,total effective rate in control group was 73.3%（33/45）,the difference was statistically significant（P 0.05）.Length of hospital stay in treatment group [（19.69 ±3.72） d] were shorter than those in control group [（27.35 ±8.06） d],cost of treatment in treatment group [（3.42±1.64）×104 yuan] were lower than those in control group [（8.53±3.73）×104 yuan],the differences were statistically significant（P 0.05）.No serious complication was found in treatment group.Conclusion Fiber bronchoscopy examination and broncho alveolar are financial,effective and safe choice for patients with refracto ry pneumonia and has less serious adverse reaction.
出处
《中国医药导报》
CAS
2013年第18期50-51,54,共3页
China Medical Herald
基金
国家自然科学基金资助项目(编号81070004)
关键词
支气管肺泡灌洗
难治性肺炎
纤维支气管镜
临床疗效
安全性
Refractory pneumonia
Fiber bronchoscopy examination
Broncho alveolar lavage
Clinical effect
Safety
