摘要
目的了解胰岛素抵抗（ＩＲ）与代谢紊乱的关系。方法对７７例３５～６２岁人群的ＩＲ与各种代谢紊乱的关系进行调查。以ＨＯＭＡ计算公式：空腹血浆胰岛素（ｍＵ／Ｌ）ｘ空腹血浆葡萄糖（ｍｍｏｌ／Ｌ）／２２．５计算，其值＞２．７７，定为ＩＲ。结果ＩＲ组３８例，非ＩＲ组３９例。两组间ＦＢＳ无显著差异，而ＨＯＭＡＩＲ值及ＦＰＩＮＳ值，高血压、高甘油三酯、高胆固醇、超重、脂肪肝的发生率均有显著差异；二种以上代谢紊乱者，其ＩＲ的发生率明显高于没有或仅有一种代谢紊乱者。结论ＩＲ普遍存在于各种代谢紊乱的疾病中，是影响代谢紊乱的危险因素。 ［
Objective To study the correlation between insulin resistance (IR) and metabolic disorders. Methods 77 cases at the age ranged from 35 to 62 years were randomly divided into IR (n > 2. 27) and non - IR (n < 2. 27) groups so as to calculate the IR by using the formula HOMA: fasting serum insulin mv/L X fasting plasma glucose (mmol/L) /22. 5. Results No statistical difference was found in FBS between the two groups but significant differences were revealed in the values of HOMA IR, cholesterol, triglycerides, fasting serum insulin between the two groups (P < 0. 01 ). IR incidences in the cases with two or more metabolic disorders were signif- icantly higher than those with one or no metabolic disorders. Conclusion Insulin resistance was one of the risk factors bringing about metabolic disorders.
出处
《浙江临床医学》
2000年第6期373-374,共2页
Zhejiang Clinical Medical Journal
