摘要
目的 探讨硬膜外腔应用吗啡超前镇痛的临床意义 .方法 选择硬膜外阻滞行腹部手术患者 6 9例 ,随机分成两组 ,均经硬膜外导管注入用生理盐水稀释至 5 m L的吗啡 2mg, 组于术毕缝皮前 , 组于术后阻滞消退后 .结果 两组镇痛作用时间和节段数相仿 ,镇痛效果优、良率均为 10 0 .0 % .两组术后 48h内镇痛药应用率和恶心、呕吐、瘙痒的发生率相似 .尿潴留发生率 组为 42 .1% , 组为 12 .9% (P<0 .0 5 ) .结论 应用吗啡行超前镇痛 ,其术后镇痛效果与出现疼痛后再应用比较 ,无明显差异 ;
AIM To investigate the clinical value of preemptive analgesia with epidural morphine. METHODS 69 patients undergoing elective abdominal surgery with epidural anesthesia were randomized into two groups (Groups I and II) and were injected with 2 mg of morphine in 5 mL normal saline via epidural catheter. Group Ⅰreceived the injection epidurally at the end of surgery and Group Ⅱreceived the injection after epidural blockade disappeared. RESULTS The analgesic duration and segmental numbers of the two groups were similar. The percentages of excellent and good analgesic effects were 100.0% in the two groups. In the incidence of receiving other analgesic medication and nausea, vomitting, itching, there was no difference between the two groups during the postoperative 48 h observation. The incidences of urine retention in the two groups were 42.1% and 12.9% respectively ( P <0.05). CONCLUSION The preemptive analgesia with epidural morphine is not necessarily more advantageous than the postoperative analgesia. Instead, it might increase the incidence of urine retention.
出处
《第四军医大学学报》
2000年第8期989-990,共2页
Journal of the Fourth Military Medical University
关键词
硬膜外腔阻滞
吗啡
超前镇痛
epidural space
morphine
pre emptive analgesia
