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多层螺旋CT常规扫描与CT灌注成像对胰腺癌的研究 被引量:9

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摘要 目的多层螺旋CT平扫、多期增强扫描和CT灌注成像对胰腺癌诊断价值。方法 45例患者行CT检查;采用GE Light Speed Pro 32多层螺旋CT机行胰腺平扫、多期增强及CT灌注检查。CT增强及灌注采用高压注射器肘静脉通道注射,以5.0ml/s的速度团注非离子型碘造影剂50ml,采用电影模式(每圈0.55),分析病灶和正常胰腺组织的血流量(BF)、血容量(BV)、平均通过时间(MTT)和表面通透性(PS)均值;常规增强扫描期相分为:动脉期25s,胰腺期45s,门脉期70s。结果 45例患者中,胰头癌17例,胰颈癌2例、钩突癌6例、胰体癌8例、胰尾癌7例,累及胰体尾胰腺癌5例。共31例取得病理。平扫期16例呈等密度;动脉期8例呈等密度;胰腺期1例呈等密度;门脉期2例呈等密度。平扫、动脉期、胰腺期及门脉期各期对胰腺病变的检出率差异有统计学意义(χ2=24.880,P=0.000)。动脉期、胰腺期及门脉期病灶与正常胰腺组织的CT值及CT差值有统计学意义(P<0.05)。癌灶与正常胰腺组织间的BF、BV、MTT及PS值均差异有统计学意义(P<0.05),胰腺癌的BF、BV及PS值低于正常胰腺组织,而MTT值则高于正常胰腺组织。结论多层螺旋CT平扫及多期增强扫描对胰腺病变的检出率胰腺期最高,增强扫描多期明显高于平扫期;多层螺旋CT灌注成像结果显示胰腺癌的灌注参数BF、BV及PS值低于正常胰腺组织,而MTT值则高于正常胰腺组织。
出处 《河北医药》 CAS 2013年第12期1783-1785,共3页 Hebei Medical Journal
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  • 1赵心明,周纯武,吴宁,罗德红,黄遥,王建卫,孙伟,梁颖.胰腺多层螺旋CT灌注研究[J].中华放射学杂志,2003,37(9):845-849. 被引量:90
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