摘要
以溴化钠、仲丁醇为原料,水为溶剂,以追加的方式投入浓硫酸,合成了溴代仲丁烷。考察了不同反应条件对产率的影响,得出适宜的反应条件:溴化钠用量为86g,仲丁醇用量为31g(nNaBr∶nC4H9OH=1∶0.5),浓硫酸用量为196g,水用量为114g(即稀释后硫酸浓度为62%),浓硫酸追加量为26g,回流反应55min,产率可达71%以上。最终产物经气相色谱分析得溴代仲丁烷产物含量为89.3%,并对产物进行了红外表征。
2-Bromobutane was synthesized from sodium bromide and isobutyl alcohol by superadding concentrated sulphuric acid in water. Different affecting factors were investigated. The optimum reaction conditions were：sodium bromide was 86 g, isobutyl alcohol was 31 g（nNoBr：Nc4H9OH=1：0.5）, concentrated sulphuric acid was 196 g,water was 114 g （the concentration of sulphuric acid was 62% after dilution）, additional concentrated sulphuric acid was 26 g. After refluxing for 55 min,more than 71 percent yield of 2- bromobutane was obtained. Finally, the product content was 89.3 percent analyzed by GC. The product was characterized by IR.
出处
《化学世界》
CAS
CSCD
北大核心
2013年第6期356-358,362,共4页
Chemical World
关键词
溴代仲丁烷
溴化钠
仲丁醇
浓硫酸
2-bromobutane
sodium bromide
isobutyl alcohol
concentrated sulphuric acid
