摘要
目的了解衡阳地区生殖道感染妇女支原体感染状况及其对药物的敏感性。方法应用商业化的试剂盒,对2 690例生殖道感染的妇女进行支原体培养和药物敏感试验。结果 2 690例生殖道感染妇女的支原体总感染率为48.3%,解脲脲原体单独感染最常见(31.7%),21～30岁年龄段支原体感染率最高(61.4%)。药敏试验结果表明,解脲脲原体仅对交沙霉素、普那霉素、强力霉素及克拉霉素敏感,人型支原体仅对强力霉素、普那霉素及交沙霉素敏感,解脲脲原体与人型支原体混合感染仅对强力霉素、普那霉素及交沙霉素敏感。结论本地区生殖道感染妇女支原体感染率较高,耐药情况与其它地区存在明显差异,在治疗前建议进行药敏实验。
Objective To investigate the prevalence and antimicrobial susceptibility of Ureaplasma urealyticum（Uu） and Mycoplasma hominis（Mh） in Chinese women with genital infection from Hengyang.Methods 2,690 Chinese women with genital infection between January 2010 and December 2012 in Hengyang were enrolled in this study.Uu or Mh was isolated from the patients and subjected to antimicrobial susceptibility tests.Results The overall positive incidence of genital mycoplasma was 48.3%.The most common pattern was Uu single infection（31.7%）.The highest infection rate by genital mycoplasmas was found in young women（age range：21~30 years）.Overall,Uu exhibited high susceptibility to josamycin,pristinamycin,doxycycline,and clarithromycin,while Mh exhibited high susceptibility to doxycycline,pristinamycin,and josamycin.UU-MH co-infection exhibited high susceptibility to doxycycline,pristinamycin,and josamycin.Conclusions The infection rates of mycoplasmas in female genital were higher in this region.Due to geographic differences in antibiotic resistance,local in-vitro susceptibility testing is recommended to avoid failure of therapy.
出处
《中南医学科学杂志》
CAS
2013年第3期293-296,共4页
Medical Science Journal of Central South China
关键词
生殖道感染
解脲支原体
人型支原体
药物敏感性
genital infectious diseases
Ureaplasma urealyticum
Mycoplasma hominis
antimicrobial susceptibility
