摘要
目前国内外关于左侧心力衰竭相关性肺动脉高压的研究较少,其发病率、病理生理机制和治疗方法尚缺乏有效的数据,而其导致的预后又较差,需加强对此类疾病的认识。鉴于此,现就左侧心力衰竭相关性肺动脉高压的病因(如高血压、缺血性心脏病等)、发病机制(如细胞因素、分子因素等)、临床特点(如危险因素、临床特征等)及治疗方法等(如吸入一氧化氮、依前列醇类药物、内皮素受体拮抗剂、5型磷酸二酯酶抑制剂、干细胞治疗等)的研究进展予以简单的介绍。
The research of pulmonary hypertension caused by left heart failure is lack at present, and there is little valid data for its prevalence, physiopathological mechanism and treatment, moreover, its progno- sis is poor. It is necessary to improve the research of pulmonary hypertension. Here is to make a review of the research progress of pulmonary hypertension caused by left heart failure, such as its etiology（ such as hyper- tension, isehemie heart disease etc. ） , pathogenesis （cell factor, molecular factor） , clinical features （such as risk factors, clinical features etc. ） and treatment（ such as inhalation of NO, epoprostenol, endothelin receptor antagonists, phosphodiesterase type 5 inhibitors, stem cell therapy, etc. ）.
出处
《医学综述》
2013年第11期2002-2005,共4页
Medical Recapitulate
关键词
肺动脉高压
左侧心力衰竭
药物治疗
干细胞治疗
Pulmonary hypertension
Left heart failure
/）rug therapy
Stem cell therapy
