摘要
血浆(1,3)-β-D葡聚糖(BG)和半乳甘露聚糖抗原(GM)存在于不同真菌的细胞壁中。作为真菌细胞壁表面的抗原性标志物,它们可通过酶联免疫分析等方法进行检测。该检测方法较痰培养等方法快捷、敏感性及特异性更高,且具有无创性,可用于侵袭性真菌感染(IFI)的早期诊断,同时对于疾病疗效的监测及评价预后有较高的价值,近年来已越来越广泛地应用于临床。
Plasma （ 1,3 ） -β-D-glucan （BG） and galactomannan （ GM ） are major constituents of different fungal cell walls. As antigenicity markers in the surface of fungal cell walls, they can be tested by enzyme- linked immunoassay. Compared with sputum culture, the test is a rapid method of collecting antigen concen- tration with high sensitivity, specificity and noninvasiveness, which has contributed to the early diagnosis of invasive fungal infection（IFt）. Besides,it has great value for monitoring curative effect and evaluating prog- nosis, therefore, it has been more and more widely applied in clinical in recent years.
出处
《医学综述》
2013年第11期1960-1963,共4页
Medical Recapitulate
