摘要
C反应蛋白(CRP)是一种由肝脏产生的急性时相蛋白,可用免疫学方法进行测定。脑梗死的重要病理基础是动脉粥样硬化,而CRP和脂质代谢紊乱则是动脉粥样硬化发生、发展的重要启动子。通过对CRP及动脉粥样硬化致病机制、他汀类药物作用的研究,认为他汀类药物在脑梗死的防治方面具有不可替代的作用。该文就CRP的生物学特征、他汀类药物对CRP及动脉粥样硬化性脑梗死的相互关系进行综述。
As an acute phase protein, C-reactive protein（CRP） is mainly produced by the liver, and can be measured by immunological method. Atherosclerosis,as the most important pathological basis of cerebral infarction, in development of which CRP and ＇lipid metabolism disorder play the role of key promoters. Based on the research of CRP and pathogenic mechanism of atherosclerosis, statin drug action, it＇s considered that statins have an irreplaceable role in the prevention and treatment of atherosclerosis and cerebral infarction. Here is to make a review of the biologicaI characteristics of CRP, the interrelation between statins, CRP and atherosclerotic cerebral infarction.
出处
《医学综述》
2013年第11期1924-1927,共4页
Medical Recapitulate
基金
湖南省卫生厅项目(2B2009118)
