摘要
目的:探讨女性冠心病危险因素。方法:选取女性冠心病(CHD)245例为女性病例组和男性冠心病636例为男性病例组,以及女性非冠心病293例为女性对照组,收集性别、年龄、体质指数、冠心病家族史、吸烟史、饮酒史、糖尿病史、高血压史、总胆固醇和甘油三酯等冠心病危险因素,分析女性冠心病危险因素的特点。结果:非条件Logistic回归分析发现,在调整混杂因素后,女性病例组与女性对照组比较,高血压史、糖尿病史和吸烟史是女性CHD的主要危险因素(P<0.0001、P=0.005和P=0.029);女性病例组与男性病例组比较,总胆固醇使女性CHD危险性显著升高(OR=1.267,95%CI为1.056～1.519,P=0.011),而吸烟史和饮酒史使男性CHD危险性显著升高(P<0.0001和P=0.042)。结论:女性CHD预防重点为控制高血压、防治糖尿病和降低总胆固醇。
Objective:To analyze coronary risk factors of female patients with coronary heart disease.Methods:Both the group of 245female patients and the group of 636male patients with coronary heart disease(CHD) as the case group and 293female without CHD as the control group were enrolled.Coronary risk factors,such as gender,age,body mass index,family history of CHD,smoking,History of alcohol,diabetes mellitus,hypertension,total cholesterol and triglycerides were collected.The data were subsequently compared.Results:The analysis showed that the major coronary risk factors in female were hypertension,diabetes mellitus and smoking.However,When the female patient group was compared with the male patient group with coronary risk factors,total cholesterol was found significantly increasing the risk of CHD in female patients(P =0.011),and conversely smoking and drinking elevated significantly the risk in male patients(P<0.0001and P= 0.042).Conclusion:The emphasis of CHD preventive intervention in the female should be on controlling hypertension,diabetes mellitus and total cholesterol.
基金
荆州市科技局2011年立项项目(201103)
关键词
冠心病
危险因素
女性
coronary heart disease
risk factors
female
