摘要
目的对宫颈活检诊断为宫颈上皮内瘤变Ⅲ级(CIN)Ⅲ的围绝经期妇女治疗方法进行研究。方法对2010年1月至2012年1月孝感市中心医院诊断为CINⅢ的围绝经期妇女152例进行研究,按照患者意愿分为两组:宫颈冷刀锥切术(CKC)组65例、宫颈环形电切术(LEEP)组87例,比较两种手术方法的特点。结果 LEEP组手术时间、出血量及切口愈合时间均小于CKC组,差异均有统计学意义(P<0.05)。LEEP组切缘阳性率16.1%(14/87),CKC组切缘阳性率4.6%(3/65),二者比较差异有统计学意义(χ2=4.933,P=0.026)。两组患者全子宫切除术后病理均未升级,其中LEEP组残留宫颈阳性率为24.3%(17/70),CKC组残留宫颈阳性率为8.2%(4/49),比较差异有统计学意义(χ2=5.155,P=0.023)。结论两种方法均可用于诊断为CINⅢ的围绝经期妇女,但对于随访条件差的CINⅢ的围绝经期妇女,建议选择CKC。
Objective To study the treatment of CIN Ⅲ by cervical biopsy in pefimenopausal women. Methods One hundred and fifty-two perimenopansal women in Xiaogan Center Hospital from Jan. 2010 to Jan. 2012 diagnosed as CIN Ⅲ were divided into two groups in accordance with the wishes of patients：cervi-cal cold knife conization（ CKC group）65 cases, and cervical loop electrosurgical excision procedure （LEEP group） 87 cases, the characteristics of the two surgical techniques were compared. Results Operative time, amount of bleeding and wound healing time were less in the LEEP group than the CKC group, with statistical-ly significant difference（ P 〈 0.05 ）. Positive margin rate in the LEEP group was 16.1% （ 14/87 ） , in the CKC group was 4.6% （ 3/65 ） , there was statistically significant difference （ X^2 = 4. 933, P = 0. 026 ）. Hyster-ectomy pathology were not upgraded in both groups. The positive residual cervical in the LEEP group was 24.3% （17/70） and was 8.2% （4/49） in the CKC group ,there was statistically significant difference（ X^2 = 5. 155,P = 0. 023 ）. Conclusion Both methods can be used for the treatment of CIN Ⅲ in perimenopausal women, hut for perimenopausal women with CIN Ill for poor follow-up, it is recommended to choose the CKC surgery.
出处
《医学综述》
2013年第12期2252-2254,共3页
Medical Recapitulate
关键词
围绝经期
宫颈上皮内瘤变
宫颈冷刀锥切术
宫颈环形电切术
宫颈癌
Perimenopausal period
Cervical intraepithelial neoplasia
Cervical cold knife conization
Cervical loop electrosurgical excision procedure
Cervical cancer
