摘要
超敏C反应蛋白(hs-CRP)是冠状动脉粥样硬化性心脏病(冠心病)发生和演变过程中的关键因素,在各种类型的冠心病患者中,血清hs-CRP浓度均升高。hs-CRP在冠状动脉粥样硬化的发病机制中发挥着十分重要的作用。冠状动脉粥样硬化实质上是一个慢性炎症的发生、发展过程,而hs-CRP是由白细胞介素6刺激肝脏产生的急性时相反应蛋白,也是导致心血管疾病的直接致病因素,是与动脉粥样硬化发生和演变有关的促炎因子,并可以预测未来心血管事件的发生,从而为冠心病的监测、临床诊断、治疗及预后提供重要的参考价值。
High sensitivity C-reactive protein（hs-CRP） is a key factor for coronary heart disease and its evolution; hs-CRP serum concentrations were elevated in various coronary heart diseases, hs-CRP has an important role in the pathogenesis of coronary atherosclerosis which provides an important reference for the clinical diagnosis,treatment and prognosis. Coronary heart disease artery atherosclerosis which is essentially the development process of chronic inflammatory reaction, and hs-CRP, an acute phase protein stimulated by interleukin-6 produced from the liver, which is also a direct causal factor for cardiovascular disease, an inflammation-promoting factor for atherosclerosis occurrence and evolution, and can be highly predictive of future cardiovascular events, providing important references for the monitoring, clinical diagnosis, treatment and prognosis.
出处
《医学综述》
2013年第12期2133-2135,共3页
Medical Recapitulate
关键词
超敏C反应蛋白
冠心病
炎症
High-sensitivity C-reactive protein
Coronary heart disease
Inflammation
