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支气管肺发育不良的分子水平及发病机制的研究进展 被引量：4

Study Advances in Molecular Pathogenesis of Bronchopulmonary Dysplasia
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摘要 随着早产儿救治成活率的不断提高,支气管肺发育不良(BPD)的病理改变、分型等也随之发生了改变。BPD可能是早产、慢性氧暴露、炎症等多因素共同作用的结果,是婴幼儿时期慢性呼吸系统疾病的主要病因和死亡原因。BPD的发病机制是新生儿医学的研究热点。该文就BPD的分子水平发病机制、相关基因在BPD发生、发展中的调节作用等相关研究进展予以综述。 With the improvement of premature infants treatment successful rate, the pathological changes and the typing of bronchopulmonary dysplasia（BPD） will also be changed. BPD might be the result of prema-ture birth, chronic oxygen exposure, inflammation and many other factors. It is not only the major cause of the chronic respiratory diseases for infants, but also the major cause of death for infants. The pathogenesis of BPD is a hot spot in neonatology. Here reviews the research progress of molecular level pathogcnesis and related genes in BPD onset and development.
作者 张华 刘漫君 全裕凤
机构地区 桂林医学院附属医院新生儿科
出处 《医学综述》 2013年第12期2121-2123,共3页 Medical Recapitulate
基金 广西壮族自治区卫生厅重点课题(重2011011)
关键词 支气管肺发育不良 分子水平发病机制 遗传易患性 Bronchopulmonary dysplasia Molecular level pathogenesis Genetic susceptibility
分类号 R725.6 [医药卫生—儿科]
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共引文献52

同被引文献53

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医学综述
2013年 第12期

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