期刊文献+

沙利度胺联合环磷酰胺和地塞米松治疗复发难治多发性骨髓瘤 被引量:7

Combination Chemotherapy of Thalidomide Cyclophosphamide and Dexamethasone in Relapsed and Refractory Multiple Myeloma
暂未订购
导出
摘要 回顾分析36例复发、难治多发性骨髓瘤(MM)患者中沙利度胺、环磷酰胺、地塞米松(CTD)联合化疗的疗效及不良反应。7例(19.5%)完全缓解(CR),19例(52.8%)部分缓解(PR),3例(8.3%)微小缓解(MR),3例(8.3%)病情稳定(SD),4例(11.1%)疾病进展。总反应率为80.6%。认为该治疗不良反应较小,患者耐受性好。
出处 《中国医科大学学报》 CAS CSCD 北大核心 2013年第6期564-566,共3页 Journal of China Medical University
基金 辽宁省科学技术计划项目(2010225032)
  • 相关文献

参考文献5

二级参考文献24

  • 1Alexanian R, Haut A, Khan Au, et al. Treatment for multiple myelo-ma,combimation chemotherapy with different melphalan dose regi- mens[J]. JAMA, 1969,208(9): 1680-1685.
  • 2Singhal S, Mehta J, Desikan R, et al. Antitumoractivity of thalidomide in refractory muhiple myeloma [ J ]. N Eng J Med, 1999,341 (21) : 1565-1571.
  • 3Palumbo A, Facon T, Sonneveld P, et al. Thalidomide for treatment of multiple myelomal : 10 years later [J]. Blood, 2008,111 (8) : 3968 - 3977.
  • 4Hulin C,Facon T,Rodon P,et al. Efficacy of melphalan and pred- nisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma:IFM 01/01 Trial [J]. J Clin Oncol, 2009,27(22) : 3664-3670.
  • 5KANE RC,BROSS PF,FARRELL AT,et al. Velcade: U.S.FDA approval for the treatment of multiple myeloma progressing on prior therapy [ J ].Oncologist, 2003,8(6) : 508-513.
  • 6GREIPP PR, SAN MIGUEL, DURIE BG, et al.International staging system for multiple myeloma [ J].J Clin Oncol, 2005,23 (15) : 3412- 3420.
  • 7BLADE J,SAMSON D,REECE D,et al.Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haematopoietic stem cell transplantation[ J].Br J Haematol, 1998,102(5 ) : 1115-1123.
  • 8PARAMORE A,FRANTZ S.Bortezomib [J].Nat Rev Drug Discov, 2003,2(8):611-612.
  • 9ANTONIO PALUMBO,MARIA TERESA AMBROSINI. Bortezomib, melphalan,prednisone,and thalidomide for relapsed multiple myeloma [ J].Blood, 2007(109) :2767-2772.
  • 10RICHARDSON PG,BARLOGIE B,BERENSON J,et al.A Phase 2 study of bortezomib in relapsed refractory myeloma [J].N Engl J Med, 2003,348 : 2609-2617.

共引文献11

同被引文献64

  • 1Lee A Y,Levine M N.Venous thromboembolism and cancer:Risks and outcomes[J] .Circulation,2003,107 (23Supple 1):117-121.
  • 2Musallam K M,Dahdaleh F S,Shamseddine A l,et al.Incidence and prophylaxis of venous thromboembolic events in multiplemveloma patients receiving immunomodulatory therapy[J] .Tbromb Res,2009,123(5):679-686.
  • 3Zangari M,Tricot G,Polavaram L,et al.Survival effect of venous thromboembolism in patients with multiple myeloma treated with lenalidomide and high-dose dexamethasone[J] .J Clin Oncol,2010,28(1):132-135.
  • 4Smith R A,Cokkinides V,Eyre H J.American Cancer Society guidelines for the early detection of cancer,2006[J] .CA Cancer J Clin,2006,56(1):11-25.
  • 5Shimizu K,Itoh J.A possible link between Trousseau's syndrome and tissue factor producing plasma cells[J] .Am J Hematol,2009,84(6):382-385.
  • 6Auwerda J J,Sonneveld P,de Maat M P,et al.Prothrombotic coagulation abnormalities in patients with newly diagnosed multiple myeloma[J] .Haematologica,2007,92(2):279-280.
  • 7De Lucia D,De Vita F,Orditura M,et al.Hypercoagulable state in patients with advanced gastrointestinal cancer:evidence for an acquired resistance to activated protein C[J] .Tumori,1997,83(6):948-952.
  • 8Green D,Maliekel K,Sushko E,et al.Activated protein C resistance in cancer patients[J] .Haemostasis,1997,27(3):112-118.
  • 9Haim N,Lanir N,Hoffman R,et al.Acquired activated protein C resistance is common in cancer patients and is associated with venous thromboembolism[J] .Am J Med,2001,110(2):91-96.
  • 10Zangari M,Saghafifar F,Mehta P,et al.The blood coagulation mechanism in multiple myeloma[J] .Semin Thromb Hemost,2003,29(3):275-282.

引证文献7

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部