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重症医学科医院感染病原菌分布及耐药性分析 被引量:19

Distribution and drug resistance of pathogenic bacteria causing nosocomial infections in department of critical care medicine
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摘要 目的了解重症医学科医院感染流行病学特点及细菌耐药性。方法对医院重症医学科2009年6月-2011年11月所分离的病原菌分布、构成及耐药性进行回顾性分析。结果重症医学科共有141例患者发生医院感染,感染率为16.99%;共分离出病原菌666株,以革兰阴性菌为主616株占92.49%,其中比例最高为鲍氏不动杆菌290株占43.54%,其次铜绿假单胞菌145株占21.77%;产气肠杆菌75株占11.26%;革兰阳性菌50株占7.51%,其中屎肠球菌24株占3.60%。结论革兰阴性杆菌仍为重症医学科医院感染的主要病原菌,且呈多药耐药性,应采取行之有效的干预对策,控制细菌耐药性迅速增长的不良趋势。 OBJECTIVE To investigate the epidemiology characteristics and bacterial drug resistance of hospital- acquired infections in the department of critical care medicine. METHODS The distribution, composition and drug resistance of the pathogens isolated from clinical specimens between Jun 2009 and Nov 2011 were retrospectively analyzed. RESULTS A total of 141 patients (16. 99%) suffered from hospital--acquired infections. Among 666 strains of pathogens isolated, there were 616 (92.49 %) strains of gram-negative bacteria and 50 (7.51%) strains of gram-positive bacteria. Acinetobacter baumannii was the predominant species of gram-negative bacteria (290 strains 43.54%), followed by Pseudornonas aeruginosa ( 145 strains, 21.77%) and Enterobacter aerogenes (75 strains, 11.26 %). There were 24 (3. 60 %) strains of Enterococcus faecium among the gram-positive bacteria. CONCLUSION The gram-negative bacilli are the main pathogens causing nosocomial infections in the department of critical care medicine and are multidrug-resistant. It is necessary to take effective interventions to control the increasing tendency of bacterial drug resistance.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2013年第12期3009-3011,共3页 Chinese Journal of Nosocomiology
关键词 重症医学科 医院感染 病原菌 耐药性 Department of critical care medicine Nosocomial infection Pathogenic bacteria Drug resistance
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