摘要
目的:研究术前预防性营养支持对有营养风险的肝胆管结石病病患者术后的影响,为临床上合理应用营养支持提供临床指导。方法:依据入选及排除标准选取我院共60例肝胆管结石病病患者做研究对象,采用术前肠外营养进行营养支持(为实验组);与同期进行手术治疗的60例肠内营养肝胆管结石病病患者做对照组,观察两组术前、术后肝功能指标变化,血清白蛋白、前白蛋白变化,并发症发生率、死亡率情况,并进行对比分析。结果:两组术后2d AST、ALT、TBIL指标明显高于术前,差异明显有统计学意义(P<0.05)。两组间AST、ALT、TBIL、DBIL术前、术后2 d比较无明显差异,无统计学意义(P<0.05);术后8d对照组明显低于实验组(P<0.05)。两组术后1 d血清白蛋白(ALB)、前白蛋白(PAB)均较术前显著下降(P<0.05);两组术后8d血清白蛋白(ALB)、前白蛋白(PAB)均有明显增高,差异明显有统计学意义(P<0.05)。两组并发症发生率比较差异明显,有统计学意义(P<0.05)。结论:对于有营养风险的肝胆管结石病病患者采取恰当预防性的营养支持,有降低手术对肝功能的影响、减少不良并发症发生率、降低死亡率的明显效果。
Objective： To investigate the effect of prevention of preoperative nutritional support of hepatobiliary nutrition tube on patients with gallstone disease risk influence clinical outcome,and provide guidance for clinical rational use of nutritional support.Methods： According to the inclusion and exclusion criteria,a total of 60 patients with hepatolithiasis,in our hospital,were chosen as research object,and parenteral nutrition nutritional support was used;60 cases of intestinal operation treatment of enteral nutrition in patients with hepatolithiasis were chosen as control group.The changes of liver function,serum albumin,prealbumin changes,complications,mortality in the two groups were detected before and after the operation.Results： AST,ALT,TBIL index in the two groups of 2D after operation were significantly higher than those in the preoperative,and the difference was statistically significant（P0.05）.AST,ALT,TBIL,DBIL before surgery between the two groups had no significant difference（P0.05）.Postoperative 8D in control group was significantly lower than that in the experimental group（P0.05）.Postoperative 1D（ALB）,serum albumin,prealbumin（PAB） in two groups were significantly lower than those before surgery（P0.05）.Postoperative 8D serum albumin（ALB）,prealbumin（PAB） in two groups were significantly increased,significant difference was statistically significant（P0.05）.Complications in two groups were significantly different,with statistical significance（P0.05）.Conclusions： Appropriate preventive nutritional support to hepatolithiasis patients at nutritious risk,can help to reduce the impact of surgery on liver function,reduce the incidence of adverse complications,and reduce mortality effectively.
出处
《现代生物医学进展》
CAS
2013年第15期2947-2950,共4页
Progress in Modern Biomedicine
基金
重庆市万州区科学技术(201103026)
关键词
肠外营养
肝胆管结石病病
营养
影响
Parenteral nutrition
Hepatolithiasis
Nutrition
Influence
