期刊文献+

致癌物参与肿瘤转移相关分子机制

暂未订购
导出
摘要 根据国际癌症研究中心(IARC)统计资料,2011年全球新发肿瘤病例为1770万,肿瘤死亡病例数为760万。由于其高发病率和病死率,肿瘤成为全球最大的公共卫生问题之一,极大地危害着人类的健康。
出处 《华夏医学》 CAS 2013年第2期407-411,共5页 Acta Medicinae Sinica
基金 国家自然科学基金(81071718 30973400)
  • 相关文献

参考文献20

  • 1Hanahan D,Weinberg R A. The hallmarks of cancer[J].Cell,2000,100(1):57-70.
  • 2李桂源,熊炜,武明花,等.现代肿瘤学基础[M].北京:科学出版社,2011:25-78.
  • 3彭亦良,梁后杰.癌细胞运动与迁移的分子机制[J].中国生物化学与分子生物学报,2006,22(10):794-798. 被引量:19
  • 4Tang F,Zou F,Peng Z,et al . N,N,-Dinitrosopipera-zine-mediated ezrin protein phosphorylation via activationof rho kinase and protein kinase C is involved in metasta-sis of nasopharyngeal carcinoma 6-10B cells [J]. BiolChem,2011,286(42):33956-33957.
  • 5申志华,陈小毅,陈锦,邓惠华,揭伟.EBV-LMP1上调Ezrin表达对鼻咽癌细胞转移潜能的影响[J].癌症,2008,27(2):165-169. 被引量:16
  • 6Alice Limoncielt Anja Wilmes,Lydia Aschauer,et al.Oxidative stress induced by potassium bromate exposureresults in altered tight junction protein expression in renalproximal tubule cells [J]. Arch Toxicol,2012,86(11):174M751.
  • 7Hu C T,Wu J R,Cheng C C,et al. Reactive oxygen spe-cies-mediated PKC and integrin signaling promotes tumorprogression of human hepatoma HepG2[J]. Clin Exp Me-tastasis,2011,28(8) :851-863.
  • 8Mowla S,Pinnock R,Leaner V,et al. PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributesto breast cancer cell migration [J]. Biochem J,2011,433:145-153.
  • 9J Shen,L Xu,T K Owonikoko,et al. NNK promotesmigration and invasion of lung cancer cells through activa-tion of c-Src/PKCt/FAK loop[J]. Cancer Letters,2012,318(1):106-113.
  • 10Hung Y H,Hung W C. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone(NNK) enhances invasiveness oflung cancer cells by upregulating contactin-1 via the 0:7nicotinic acetylcholine receptor/ERK signaling pathway[J]. Chemico-Biological Interactions,2009,179( 2-3 ):154-159.

二级参考文献48

  • 1孙琦蛮,樊嘉,刘银坤,周俭,余耀,邱双健,吴志全.Ezrin在肝癌中的表达及其与肿瘤黏附、侵袭和门静脉癌栓的关系[J].复旦学报(医学版),2005,32(2):147-150. 被引量:22
  • 2Yamaguchi H,Wyckoff J,Condeelis J.Cell migration in tumors[J].Curr Opin Cell Biol,2005,17(5):559-564
  • 3Wang W,Goswami S,Sahai E,et al.Tumor cells caught in the act of invading:their strategy for enhanced cell motility[J].Trends Cell Biol,2005,15(3):138-145
  • 4Sahai E,Marshall C J.Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis[J].Nat Cell Biol,2003,5(8):711-719
  • 5Condeelis J,Segall J E.Intravital imaging of cell movement in tumours[J].Nat Rev Cancer,2003,3(12):921-930
  • 6Pollard T D,Borisy G G.Cellular motility driven by assembly and disassembly of actin filaments[J].Cell,2003,112(4):453-465
  • 7Friedl P.Prespecification and plasticity:shifting mechanisms of cell migration[J].Curr Opin Cell Biol,2004,16(1):14-23
  • 8Merlot S,Firtel R A.Leading the way:directional sensing through phosphatidylinositol 3-kinase and other signaling pathways[J].J Cell Sci,2003,116(Pt17):3471-3478
  • 9Wyckoff J,Wang W,Lin E Y,et al.A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors[J].Cancer Res,2004,64(19):7022-7029
  • 10Kang Y,Siegel P M,Shu W,et al.A multigenic program mediating breast cancer metastasis to bone[J].Cancer Cell,2003,3(6):537-549

共引文献34

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部