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2β-Deoxy-Kdo Is an Inhibitor of the Aralaidopsls thaliana CMP-2-Keto-3-Deoxymanno-Octulosonic Acid Synthetase, the Enzyme Required for Activation of Kdo Prior to Incorporation into Rhamnogalacturonan II 被引量：1

2β-Deoxy-Kdo Is an Inhibitor of the Aralaidopsls thaliana CMP-2-Keto-3-Deoxymanno-Octulosonic Acid Synthetase, the Enzyme Required for Activation of Kdo Prior to Incorporation into Rhamnogalacturonan II
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摘要 Dear Editor, Gram-negative bacteria utilize the acid sugar 2-keto-3-deoxymanno-octulosonic acid （Kdo） as an essential component of the lipopolysaccharide （LPS）. The enzyme CMP-Kdo synthetase （KdsB） is required to activate Kdo prior to incorporation into the LPS, utilizing Kdo and CTP to form CMP-Kdo and pyrophosphate. Dear Editor, Gram-negative bacteria utilize the acid sugar 2-keto-3-deoxymanno-octulosonic acid （Kdo） as an essential component of the lipopolysaccharide （LPS）. The enzyme CMP-Kdo synthetase （KdsB） is required to activate Kdo prior to incorporation into the LPS, utilizing Kdo and CTP to form CMP-Kdo and pyrophosphate.
作者 Kevin M. Smyth Halina Mikolajek Jorn M. Werner Alan Marchant
机构地区 Centre for Biological Sciences
出处 《Molecular Plant》 SCIE CAS CSCD 2013年第3期981-984,共4页 分子植物（英文版）
关键词 KDO 酶激活 合成酶 酶抑制剂 酮糖 酮基 拟南芥 脱氧
分类号 Q55 [生物学—生物化学] TP311.13 [自动化与计算机技术—计算机软件与理论]
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  • 1Bar-Peled, M., Urbanowicz, B.R., and O'Neill, M.A. (2012). The synthesis and origin of the pectic polysaccharide rhamnogalac- turonan Ih insights from nucleotide sugar formation and diver- sity. Front. Plant Sci. 3, 92.
  • 2Becker, B., Lommerse, J.RM., Melkonian, M., Kamerling, J.R, and Vliegenthart, J.EG. (1995). The structure of an acidic trisaccha- ride component from a cell wall polysaccharide preparation of the green alga Tetraselmis striata Butcher. Carbohyd. Res. 267, 313-321.
  • 3Delmas, E, Sdveno, M., Northey, J.G.B., Hernould, M., Lerouge, R, McCourt, R, and Chevalier, C. (2008). The synthesis of the rham- nogalacturonan II component 3-deoxy-D-manno-2-octulosonic acid (Kdo) is required for pollen tube growth and elongation. J. Exp. Bot. 59, 2639-2647.
  • 4Hammond, S.M., Claesson, A., Jansson, A.M., Larsson, L.G., Pring, B.G., Town, C.M., and Ekstr6m, B. (1987). A new class of syn- thetic antibacterials acting on lipopolysaccharide biosynthesis. Nature. 327, 730-732.
  • 5Heyes, D.J., Levy, C., Lafite, R, Roberts, I.S., Goldrick, M., Stachulski, A.V., Rossington, S.B., Stanford, D., Rigby, S.E.J., Scrutton, N.S., et al. (2009). Structure-based mechanism of CMP-2-keto-3- deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases. J. Bio. Chem. 284, 35514-35523.
  • 6Kobayashi, M., Kouzu, N., Inami, A., Toyooka, K., Konishi, Y., Matsuoka, K., and Matoh, T. (2011). Characterization of Arabidopsis CTP:3-deoxy-D-manno-2-octulosonate cytidylyl- transferase (CMP-Kdo synthetase), the enzyme that activates Kdo during rhamnogalacturonan II biosynthesis. Plant Cell Physiol. 52, 1832-1843.
  • 7Misaki, R., Kajiura, H., Fujii, K., Fujiyama, K., and Seki, T. (2009). Cloning and characterization of cytidine monophosphate-3-de- oxy-D-manno-octulosonate synthetase from Arabidopsis tha/i- aria. J. Biosci. Bioeng. 108, 527-529.
  • 8O'Neill, M.A., Eberhard, S., Albersheim, R, and Darvill, A.G. (2001). Requirement of borate cross-linking of cell wall rhamnogalac- turonan II for Arabidopsis growth. Science. 294, 846-849.
  • 9O'Neill, M.A., Ishii, T., Albersheim, R, and Darvill, A.G. (2004). Rhamnogalacturonan II: structure and function of a borate cross-linked cell wall pectic polysaccharide. Annual Rev. Plant Biol. 55, 109-139.
  • 10Ray, RH., Benedict, C.D., and Grasmuk, H. (1981). Purification and characterization of cytidine 5'-triphosphate-cytidine 5"-monophosphate-3-deoxy-D-manno-octulosonate cytidylyl- transferase. J. Bacteriol. 145, 1273-1280.

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Molecular Plant
2013年 第3期

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