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肾小管上皮间充质转化发病机制的研究进展

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摘要 肾小管间质纤维化(renal interstitial fibrosis,RIF)是各种慢性肾脏病进展到终末期肾衰竭的主要病理基础。其主要病理改变表现为肾间质细胞外基质堆积、肾小管萎缩、肾间质肌成纤维细胞增多等,其过程受多种因素的共同影响,而肾间质肌成纤维细胞是合成细胞外基质的主要细胞。已有研究表明,
出处 《临床肾脏病杂志》 2013年第5期238-240,共3页 Journal Of Clinical Nephrology
基金 国家自然科学基金项目(No.81173219) 科技部中医药行业科研专项(No.201007005) 上海市科委创新行动计划项目(No.11DZ1973100) 上海市教育委员会E-研究院建设计划资助项目(No.E03008) 上海高校创新团队建设项目
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