摘要
目的:探讨采用异体脱细胞真皮基质(ADM)对鼻颅底肿瘤术后颅底缺损的重建效果。方法:应用ADM"工形夹层"法对13例晚期鼻颅底肿瘤术后颅底缺损进行Ⅰ期缺损修复,术后行鼻内镜和CT检查分析重建效果。结果:术后随访6～30个月,13例均未出现脑脊液漏、脑膜脑膨出。术后3例患者48h内出现不同程度颅内感染的症状和体征,给予抗生素联合应用,应用地塞米松抗炎,甘露醇脱水,利尿剂降低颅内压及降温、镇静等处理,2周后症状逐渐缓解。结论:采用ADM"工形夹层"法Ⅰ期重建颅底缺损,效果良好。
Objective：The purpose of this study is to explore the effect of reconstruction for the nose cranial base defects after removal of tumor with ADM.Method：Thirteen patients with the nose skull base defects after tumors resection underwent cranialbase reconstruction with ADM at the same time.Postoperatively,routine endoscopic and CT scan were performed on all patients at regular intervals.Result：The successful cranial base reconstruction was achieved in 13 patients with ADM.Intracranial infection occurred in 3 patients and recovered after two weeks postoperatively,given combination of antibiotics,dexamethasone anti-inflammatory,mannitol,reduce intracranial pressure with diuretics and cooling,sedation processing.All patients developed no delayed complications.Conclusion：Our experience has demonstrated that the cranial base reconstruction with the ADM＂工＂ shaped sandwich has harvest the satisfactory effect.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2013年第12期639-641,645,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
修复外科手术
鼻窦肿瘤
异体脱细胞真皮基质
reconstructive surgical procedures
paranasal sinus neoplasms
acellular allogeneic dermal matrix
