摘要
目的研究医院感染大肠埃希菌的临床分布特征及耐药性,为合理使用抗菌药物提供参考。方法采用细菌分离鉴定和药敏试验方法,对感染病人标本中病原菌及其耐药性进行检测。结果 2010年1月-2011年7月从病人标本中共分离出大肠埃希菌486株。有236株分离自术后及开放性创口分泌物,构成比为48.56%;来自痰液和呼吸道分泌物为165株,占33.95%;从尿液中检出39株,占8.02%。检出产ESBLs菌株占40.74%,此类菌株广泛耐药。结论临床分离的大肠埃希菌主要来自伤口分泌物和痰液标本,产ESBLs菌株比例较大,且广泛耐药。
Objective To investigate the distribution and drug resistance of Escherichia coli in hospital infection so as to provide instructive suggestions for the clinical medication. Methods Bacteria separation and identification method and drug sensitivity test were used to detect the bacteria isolated from patient specimens and drug sensitivity test. Results 486 strains of Escherichia coli were isolated from patient specimens between January 2010 and July 2011. 236 strains were isola- ted from of the secretion of postoperative and open wound, accounting for 48. 56% ; 165 strains were isolated from sputum and the secretion of respiratory, accounting for 33.95% ; 39 strains were isolated from urine, accounting for 8.02%. 198 strains of ESBLs accounting for 40.74% were detected and they were extensively drug - resistant. Conclusion E. coil are mainly isolated from Postoperative and open wound in hospital infection. The ratio of ESBLs strains is comparatively large and the ESBLs strains are extensively drugresistant.
出处
《中国消毒学杂志》
CAS
北大核心
2013年第5期428-429,432,共3页
Chinese Journal of Disinfection
基金
深圳市宝安区科技局2011年科技立项(编号:20110464)
关键词
大肠埃希菌
药敏试验
超广谱Β-内酰胺酶
耐药性
Escherichia coli
drug sensitivity test
extended - Spectruml3 - lactamase
drug resistance
