摘要
目的探讨早发型子痫前期解痉抗凝疗效的临床效果。方法选取2009年11月-2012年11月期间收治的50例早发型子痫前期患者,随机分成观察组25例,对照组25例。给予对照组常规以硫酸镁解痉为主的传统治疗,给予观察组在常规硫酸镁治疗基础上加用低分子肝素抗凝综合治疗,比较两组的临床效果。结果观察组新生儿病死率4%,新生儿窒息发生率16%,并发症发生率28%;对照组新生儿病死率12%,新生儿窒息率28%,并发症发生率52%。两组在新生儿病死率、统计学差异新生儿窒息发生率以及并发症发生率上均具有统计学意义,P<0.05。结论加强对早发型子痫前期患者进行解痉、抗凝综合治疗可以提高临床疗效,值得临床推广使用。
Objective To study the clinical effect observation of therapeutic effects of anticoagulant agents on the early onset preeclampsia- eclampsia women. Methods 50 women with early onset preeclampsia-eclampsia admitted in our hospital from Nov. 2009 to Nov. 2012 were involved, who were randomLy divided into experimental group and control group （25 patients respectively）, and the treatment of the experimental group was traditional, treated with mainly magnesium sulfate, while the patients of the control group were treated with low molecular weight heparin（LMWH） anticoagulant treatment in addition to traditional treatment. Results The mortality of operated newborns was 4% and the neonatal asphyxia rate was 16% .The operative complication rate occurred in 52% .The difference was significant between the two groups,P〈0.05. Conclusion the effect of patients with therapeutic effects of anticoagulant agents on the early onset preeclampsia-eclampsia can be improved by low molecular weight heparin（LMWH） anticoagulant treatment in addition to spasmolysis, and deserves further clinical applications.
出处
《当代医学》
2013年第16期40-41,共2页
Contemporary Medicine
关键词
早发型子痫前期
解痉
抗凝
Early onset preeclampsia-eclampsia
Spasmolysis
Anticoagulant treatment
