摘要
本文报道对地方性克汀病患者进行了临床神经病学检查,包括传统的椎体神经系统检查,而且注意检查了椎体外系统,特别对智力功能做了比较精细的研究。同时观察了垂体甲状腺功能,结果表明克汀病组血清T_4值较正常对照组低而TSH值高(P<0.05)。血清hGH空腹值两组无差别,但用左旋多巴兴奋后60分钟及90分钟值克汀病组低于正常对照组(P<0.05)。运用左旋多巴刺激试验证实地方性克汀病人垂体人类生长激素储备功能差,是一个新发现,有利于对碘缺乏病史深入地研究。
Combined with the determination of pituitary and thyroid functions, neuro-pathological examinations were performed on patients with endemic cretinism in Huangzhu Community, Gansu Province. Results showed that average serum T4 in cretinist patients was lower and TSH higher than those in normal controls (P<0.05). No difference in fasting serum hGH was found between the 2 groups, however, serum hGH in cretinist patients was significantly lower (P<0.05) when L-dopa stimulation test was carried out for 60 and 90 minutes. Thus, it was first confirmed in this study that the ability to reserve hGH was very low for patients with endemic cretinism.
出处
《地方病通报》
1991年第1期66-69,共4页
Endemic Diseases Bulletin
关键词
地方性
克汀病
椎体系流
智力
Endemic cretinism
Pyramidel system
Extrapyramidal system
Intelligence
Serum T4
TSH
hGH
L-dopa stimulation test
