摘要
目的:观察逍遥丸对酒精性肝病肝郁脾虚证中医证候的疗效。方法:52例酒精性肝病肝郁脾虚型患者应用逍遥丸治疗,疗程为4周,借助中医症状分级量化表,评价其疗效并比较治疗前、后中医证候的变化。结果:①4周时中医证候疗效:痊愈34例(65.38%),显效13例(25.00%),有效5例(9.62%),无效0例。②中医证候总积分整体比较,治疗前、后5次测量之间有统计学意义,随治疗时间的延长,中医证候总积分呈下降趋势。③肋胁腹痛,腹胀、恶心、便溏4个主要症状治疗前、后5次测量之间比较均有统计学意义,每个症状的得分随治疗时间均呈下降趋势。④"肋胁腹痛"症状得分下降最快,而"便溏"症状得分下降最慢。结论:由于本研究未设对照,尽管研究结果提示逍遥丸"疗效显著",但尚需进一步严格的随机对照临床试验进行确认。
Objective ： To study the efficacy of Xiaoyao Pill on liver depression and spleen deficiency syndrome of alcoholic liver disease. Method：52 alcoholic liver disease patients with liver depression and spleen deficiency syndrome were treated with Xiaoyao Pill for 4 weeks ,to evaluate the efficacy and compare the TCM syndrome before and after treatment. Result ： After 4 weeks, the efficaey of TCM syndrome was ： （1）34 were cured （ 65.38% ） , 13 were markedly effective （ 25. 00% ） ,5 were effective（9.62% ） ,and no one was invalid. （2）The TCM syndrome total score was statistically significant between 5 measurements before and after treatment, and there was a downward trend with the duration of treatment. （3）The hypochondrial distending pain, bloating, nausea and loose stool were statistically significant between 5 measurements before and after treatment, and ＇all had a decreasing trend with the duration of treatment. （4）The symptom.score of hypochondrial distending pain decreased fastest and the loose stool decreased slowest. Conclusion：The study results suggest that Xiaoyao Pill has a good effect on the liver depression and spleen deficiency syndrome of alcoholic liver disease.
出处
《中华中医药学刊》
CAS
2013年第6期1265-1267,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金项目资助(81172734)
解放军302医院院内课题资助项目(YNKT2010012)
关键词
逍遥丸
酒精性肝病
肝郁脾虚
Xiaoyao Pill
alcoholic liver disease
depression and spleen deficiency syndrome
