摘要
目的:以冠心病稳定型心绞痛痰瘀互结证患者为研究对象,探究其理化检查结果与3个量表的关系,并希望能够为冠心病稳定型心绞痛的辨证分型研究提供新思路。方法:临床流行病学调查采用横断面调查法。运用自评量表、辨证量表、TCMSAQ-QBS量表对研究对象进行资料采集,结合血脂、血糖、心电图等29项理化指标对研究对象搜集临床资料。理化指标与各量表关系的挖掘采用相关性分析、Logistic回归、多元线性回归进行研究。结果:理化检查中11个指标与辨证量表的4个维度(脾气虚维度、痰维度、瘀维度、疾病维度)、TCMSAQ量表的4个维度(证候维度、运动耐量维度、睡眠维度、治疗满意维度)以及自评量表的2个维度(运动耐量维度、疾病维度)相关,并可建立相应的回归模型(P<0.05)。结论:冠心病稳定型心绞痛理化检查与量表在疾病的诊断、病情的评估方面具有一致性。其中空腹血糖、甘油三酯、C反应蛋白以及代表特定解剖部位心肌缺血的心电图导联与量表维度间关系为冠心病稳定型心绞痛的辨证分型研究拓展了新思路。
Objective： Stable angina pectoris with phlegm and blood stasis syndrome was taken as the research object. The relationship between physical and chemical inspections and scales were studied. It may probably provide new ideas for syndrome differentiation of stable angina pectoris. Method： The cross - sectional survey method was used in the clinical epidemiological survey. The self - rating scale, the dialectical scale and the TCMSAQ - QBS were used to collect the study data of the patients. Well 29 physical and chemical indicators such as lipids, blood glucose, ECG were taken to collect clinical data. ＂Pearson correlation analysis, Logistic regression, and multiple linear regression methods were used to study the relationship between them. Result ： 11 indicators of the physical and chemical examination dialectical were related to the four dimensions of scale of the dialectical scale（ spleen deficiency dimension, phlegm dimension, blood stasis dimension and disease dimension） ,four dimensions of the TCMSAQ- QBS （syndrome dimension, exercise tolerance dimension, sleep dimension and treatment satisfaction dimension）, and two dimensions of the self - rating scale （ exercise tolerance dimension, disease dimension）. And regression models could be built between them （P 〈 0. 05）. Conclusion： Physical and chemical examinations and scales of stable angina pectoris have consistency in the terms of the diagnosis of disease, the evaluation of the illness and the judgment of the prognosis. Furthermore, the relationship between the scale dimensions and some indicators such as fasting plasma glucose, triglycerides, C - reactive protein and the ECG for the specific anatomic sites of myocardial ischemia provides new ideas for the syndrome differentiation of coronary heart disease.
出处
《中华中医药学刊》
CAS
2013年第6期1255-1260,共6页
Chinese Archives of Traditional Chinese Medicine
基金
国家科技部"重大新药创制"专项课题资助项目(2009ZX09502-29)
关键词
冠心病
量表
理化检查
相关分析
LOGISTIC回归
多元线性回归
coronary heart disease
scale
physical and chemical inspection
correlation analysis
Logistic regression
multivariate linear regression
