摘要
目的观察对雾化吸入糖皮质激素治疗的患者采用生理盐水套餐口腔护理后口腔黏膜的反应,分析该套餐防治口腔真菌感染的疗效。方法将112例符合纳入标准的支气管哮喘伴口腔溃疡患者随机分为试验组58例,对照组54例;两组治疗原则相同,雾化吸入糖皮质激素后口腔护理试验组给予生理盐水套餐,对照组给予普通生理盐水,观察两组患者真菌感染的预后。结果试验组和对照组口腔白斑发生率分别为13.79%及55.56%,口腔真菌感染率为0.52%及37.04%,试验组较对照组明显降低,差异有统计学意义(P<0.05);口腔护理总有效率试验组86.20%,对照组44.44%,组间差异有统计学意义(P<0.05)。结论运用生理盐水套餐对使用糖皮质激素吸入剂的哮喘患者进行口腔护理,可降低口腔白斑和真菌感染发生率,促进口腔溃疡愈合。
OBJECTIVE To observe the effect of physiological saline on prevention of the oral fungal infections in the patients who received the glueocorticoids inhalation therapy and analyze the efficacy of the this program in prevention of the oral fungal infections. METHODS A total of 112 bronchial asthma patients were randomly divided into the observation group with 58 cases and the control group with 54 cases. The patients in observation group were given the physiological saline combo oral cavity nursing after glucocorticoids atomization inhalation, However,the patients in the control group were given the normal saline oral cavity nursing. The prognosis of the two groups of patients with fungal infections was observed. RESULTS The incidence rate of oral leukoplakia was 13.79% in the observation group and 55.56% in the control group,and the incidence rate of the fungal infections was 0.52% in the observation group and 37.04% in the control group, and the difference between the observation group and the control group was statistically significant （P〈0.05）. The total effective rate of oral nursing was 86.20% in the observation group and 44.44% in the control group, the difference between the two groups was statistically significant （P〈0.05）. CONCLUSION Using physiological saline for the combo oral cavity nursing can reduce the incidence rate of oral leukoplakia or the fungal infections in the severe asthma patients receiving the glu-cocorticoids inhalation therapy and can promote the healing of the oral ulcer.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第11期2681-2682,共2页
Chinese Journal of Nosocomiology
关键词
糖皮质激素
真菌感染
口腔白斑
生理盐水套餐
口腔护理
Glucocorticoids
Fungal infection
Oral leukoplakia
Physiological saline combo
Oral cavity nursing
