摘要
目的探讨硬膜外麻醉在乙型肝炎病毒(HBV)携带及感染妇科手术患者中应用效果及置管出血率,以期能为HBV携带及感染患者的手术麻醉方式的选择提供参考。方法选取在医院行妇科手术的HBV携带及感染患者各30例作为研究对象,随机选取同期肝功能正常、无HBV感染的妇科手术患者30例作为对照组,观察各组患者麻醉效果、置管过程中出血发生等指标变化。结果麻醉起效时间、麻醉完善时间HBV携带组、HBV感染组、对照组各组间比较,差异均无统计学意义;低血压、心率减慢、置管出血HBV携带组分别为10.00%、0、20.00%,HBV感染组分别为13.33%、3.33%、23.33%,对照组分别为3.33%、6.67%、3.33%,低血压、心理减慢发生率各组间比较,差异无统计学意义;置管出血率HBV携带组、HBV感染组明显高于对照组,与对照组比较,差异有统计学意义(HBV携带组与对照组t=4.04,HBV感染组与对照组t=5.19,P<0.05),HBV携带组与HBV感染组间比较差异无统计学意义;麻醉优良率HBV携带组为86.67%,HBV感染组为83.33%,对照组为93.33%,各组比较差异无统计学意义。结论 HBV携带及感染的妇科手术患者硬膜外麻醉效果与未感染HBV的妇科手术患者效果相同,置管出血率明显增加。
OBJECTIVE To investigate the effect of epidural anesthesia on the hepatitis B virus (HBV) infections in the patients undergoing gynecological surgery and the catheter bleeding rate so as to choose the effective anesthesia method for the patients with HBV infections. METHODS Totally 30 cases of patients carrying HBV and 30 cases of patients with HBV infections , who underwent the gynecologic surgery in the hospital, were selected as the study objects, and at the same time 30 patients with normal liver function but without HBV infections were select-ed as the control group; the anesthetic effect and the bleeding during the catheterization were observed. RESULTS The difference in the anesthesia onset time or anesthesia perfect time among the HBV carrying group, the HBV infection group, and the control group was not statistically significant. The incidence rates of the hypotension, slow heart rate, and catheter bleeding were respectively 10. 00%, 0. 00% and 20. 00% of the HBV carrying group, 13.33%,3.33%, and 23.33% of the HBV infection group, and 3.33%, 6.67%, and 3.33% of the con-trol group ,indicating that the difference in the ificidence rate of hypotension or slow heart rate between the three groups was not statistically significant; the incidence of catheter bleeding of the HBV carrying group or the HBV infection group was obviously higher than that of the control group, the difference was statistically significant (the HBV carrying group and the control group t= 4.04, the HBV infection group and the control group t= 5.19, P〈 0.05), but the difference between the HBV carrying group and the HBV infection group was not statistidally sig-nificantl the excellent anesthesia rate was 86. 67% in the HBV carrying group, 83.33% in the HBV infection group, and 93.33 % in the control group, the difference between the three groups was not statistically sigriificant. CONCLUSION The epidural anesthesia effect the gynecological surgery patients carrying HBV or the patients with HBV infections is as same as on the patients without HBV infections, and the incidence of catheter bleeding is increased significantly.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第11期2641-2643,共3页
Chinese Journal of Nosocomiology
关键词
乙型肝炎病毒
妇科手术
硬膜外麻醉
置管
出血
Hepatitis B virus
Gynecological surgery
Epidural anesthesia
Catheter
Bleeding