摘要
目的了解乳腺癌患者经外周穿刺中心静脉置管术(PICC)实施化疗发生导管相关性感染及相关因素,并制定对策。方法回顾性调查2010年1月-2012年1月医院170例PICC置管化疗乳腺癌患者导管相关性感染发生率及其原因。结果 170例患者中导管局部感染20例,感染率为11.8%;引起PICC感染的相关高危因素有导管留置时间、化疗疗程、换药频次、血像、基础疾病,差异有统计学意义(P<0.05);logistic回归分析提示,这些危险因素对感染影响作用大小依次为留置时间>化疗疗程>换药频次>血像>伴有糖尿病(χ2=46.28、45.52、37.04、25.23);而导管感染与穿刺次数、穿刺部位、年龄等因素无明显相关性。结论合理选择留置导管的部位,加强置管操作与维护管理、缩短导管留置时间、加强患者营养及提高免疫力,可降低导管相关性感染的发生率。
OBJECTIVE To investigate the related factors of catheter-related infections in the breast cancer chemotherapy patients with peripherally inserted central of catheter（PICC） so as to develop counter measures. METHODS The related factors of the catheter-related infections were retrospectively analyzed based on the data of 170 cases with PICC between Jan 2010 and Jan 2012. RESULTS Among 170 breast cancer patients, 20 cases were complicated with local infections, the infection incidence was 11. 8G. The PICC infections were related to the high-risk factors such as the catheter retention time, chemotherapy regimen, the frequency of dressing change, he- mogram, and underlying diseases, there was statistical difference（P^0.05）. The logistic regression analysis indi-cated that the impact of the risk factors on the infections, with the intensity from high to low, were in turn as fol-lows., retention time, chemotherapy regimen, the frequency of dressing changes, hemogram and diabetes（X^2=46. 28,45.52,37.04,25.23）; but there was no significant correlation between the catheter-related infections and the frequency of puncture, puncture sites, or age. CONCLUSION Selecting the proper location for catheter intubation, strengthening the management of intubation and catheter indwelling, shortening catheterization duration, intensif-ying the patientsr nutrition status, and improving the immunity are the effective ways to reduce the incidence of the Catheter-related infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第11期2583-2584,2603,共3页
Chinese Journal of Nosocomiology
关键词
乳腺癌
经外周穿刺中心静脉置管
感染
护理
Breast cancer
Peripherally inserted central catheter
Infection
Nursing
