摘要
目的对右美托咪定用于AECOPD合并呼吸衰竭患者无创机械通气时镇静治疗,观察其疗效。方法对7例接受无创机械通气失败的患者,使用右美托咪定对其进行镇静治疗,并观察血气分析指标、生命体征变化及最终治疗效果。结果6名患者在接受右美托咪定镇静治疗后可达到理想镇静深度,其中2名患者最终避免了气管插管而治愈。结论 NIPPV时行镇静治疗可改善人机关系,而右美托咪定可能是一种较为安全且有效的镇静药物。
Objective To observe the sedation effect of dexmedetomidine of noninvasive positive pressure ventilation （NIPPV） in the treatment of AECOPD patients complicated with respiratory failure, and to review its relevant literatures. Methods 7 AECOPD pa- tients complicated with respiratory failure, who had initially failed in N[PPV, were subsequently tranquilized by dexmedetomidine. Their blood gas analysis, vital signs and curative effect were observed. Results 6 patients had a ideal sedation after the use of dexmedetomidine and were able to cooperate with NIPPV, without major adverse reactions. 2 of them were successfully weaned from the mechanically venti- lated support without intubation. Conclusion Sedative therapy for patients undergone NIPPV therapy maybe useful, and dexemedemidine maybe is a safe and effective drug for the sedative therapy of these patients.
出处
《临床肺科杂志》
2013年第7期1178-1180,共3页
Journal of Clinical Pulmonary Medicine
关键词
右美托咪定
无创机械通气
慢性阻塞性肺病急性加重
呼吸衰竭
镇静
dexmedetomidine
noninvasive positive pressure ventilation
acute exacerbation of chronic obstructive pulmonary disease
respiratory failure
sedation
