摘要
目的：分析哮喘和慢阻肺患者院前氨茶碱中毒的临床特征，为临床安全有效地应用氨茶碱提供参考。方法：回顾分析45例院前茶碱中毒患者的临床特征，包括病人的全身情况、院前用药情况、临床表现等。结果：本组患者院前中毒发生率达12．1％，且老年患者居多，氨茶碱中毒个体差异性很大，与年龄、机体健康状况、院前用药情况密切相关。结论：茶碱用药剂量个体差异显著，易出现中毒反应。院前用药应保持高度警惕，详细询问患者用药情况，有条件应开展氨茶碱的血药浓度监测，确保临床用药安全有效。
Objective: To analyze the clinical features of pre-hospitaliration Aminophylline poisoning in asthma patients and COPD patients and offer reference to saft and effective clinical use of Aminophylline.Methods: To analyze the clinical features of 45 cases of pre-hospitalization Aminophylline poisoning patients, including general conditions, pre-hospitalization drugs usage,clinical manifestation. ResultS: The incidence rate of pre-hospitalization Aminophylline poisoning is 12.1%, and it was apt to happen in elder patients.The individual disparity of Aminophylline poisoning patients was quite large,and it was closely related to age, general conditions and pre-hospitalization drugs usage. Conclusion:The individual disparity of Aminophylline dosage was so significalntly large as to be easy to cause poisoning. It is suggested to keep high alert to drugs usage before hospitalizing, carefully inquire about drugs usage, and, if available, serum Aminophylline concentrations monitoring is recommended to ensure safe and effective usage.
出处
《广州医药》
2000年第3期13-14,共2页
Guangzhou Medical Journal
