摘要
目的探讨原发性结直肠恶性淋巴瘤临床特点及预后。方法回顾性分析33例原发性结直肠恶性淋巴瘤患者的临床资料,分析患者临床特点,采用SPSS 13.0统计软件进行数据处理,Kaplan-Meier法计算生存率,Logistic回归分析预后影响因素,2检验对生存率进行比较。结果 33例患者均接受肿瘤切除治疗,32例为非霍奇金淋巴瘤,其中28例来源于B细胞,4例来源于T细胞;1例为霍奇金淋巴瘤。总的1年、3年和5年生存率分别为87.9%、72.7%和50.0%。手术联合化疗组的3年、5年生存率分别为88.5%和61.1%,单纯手术组的3年、5年生存率分别为14.3%和0(P<0.01)。结论原发性结直肠恶性淋巴瘤临床少见,手术联合术后化疗为首选治疗方案。
Objective To investigate the clinical characteristics and the prognosis of primary color- ectal lymphoma. Methods To analyze the clinic data of 33 patients with primary colorectal lymphoma ret- rospectivly, and to analyze the clinical characteristics of these patients simultaneously, SPSS13.0 was used for data processing. Survival rate was calculated by Kaplan-Meier method, risk factors related to prognosis of primary colorectal lymphoma was analyzed by Logistic regression analysis. Survival rate was assessed with Chi-square test. Results All patients received the resection of neoplasm, 32 patients were proved the non- Hodgkin＇s lymphomas, and I patient was Hodgkin＇s lymphoma; 28 cases booted in B cell, and 4 cases boot- ed in T cell. The 1 year survival rate was 87. 9% ,3 year survival rate was 72. 7% ,and the 5 year survival rate for all cases was 50. 0%. In group surgery combined postoperative chemotherapy, 3 and 5 year survival rate was 88. 5% and 61.1% respectively; In group surgery, 3 and 5 year survival rate was 14. 3% and 0% respectively（P 〈 0. 01 ）. Conclusions primary colorectal lymphoma is a rare disease, surgery combined with postoperative chemotherapy is the preferred treatment.
出处
《中国肿瘤临床与康复》
2013年第5期417-419,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
结直肠淋巴瘤
手术
药物疗法
预后
Colorectal lymphoma
Surgery
Drug therapy
Prognosis
