摘要
目的 :观察瑞格列奈降低 2型糖尿病人的空腹血糖 ,餐后 2h血糖的作用。方法 :2型糖尿病人 68例 ,随机分为治疗组 3 4例 (男 1 8,女 1 6)及对照组 3 4例 (男 1 7,女 1 7)。采用瑞格列奈 0 .5mgpotid× 4周。结果 :能有效降低 2型糖尿病人的空腹血糖 ,餐后 2h血糖的作用。有非常显著性差异 (P <0 .0 1 ) ,尚能降低糖化血红蛋白 (P <0 .0 1 )。结论 :瑞格列奈能有效降低 2型糖尿病人的空腹血糖 ,餐后 2h血糖 ,降低血脂及糖化血红蛋白 ,且无明显副作用。
OBJECTIVE:To evaluate the therapeutic effectiveness of repaglinide in lowering the FBG and PPBG in type 2 diabetes among 68 patients.METHODS:68 cases were divided at random into two groups:Repaglinide group(34 patients,17female,17male) and Placebo controlled group(34 patients,16female and 18male).0.5mg repaglinide was taken orally before each meal in therapeutic group for 4 weeks,while the cases in control were treated by placebo.RESULTS:Repaglinide could effectively decrease the levels of FBG,PPBG and HbA1C with significant difference when compare with the placebo(P<0.01).At the meantime,it could also lower the Cholesterol and triglyceride levels when compared with the control group(P<0.01).CONCLUSION:Repaglinide was effective in lowering the levels of FBG,PPBG and HbA1C in type 2 diabetes patients without obvious side effects.
出处
《中国现代应用药学》
CAS
CSCD
2000年第3期237-238,共2页
Chinese Journal of Modern Applied Pharmacy
